Recombinant Full Length Human RALGDS Protein, C-Flag-tagged

• Cat.No.: RALGDS-1001HFL
• Product Overview: Recombinant Full Length Human RALGDS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 100.4 kDa
• AA Sequence: MVQRMWAEAAGPAGGAEPLFPGSRR SRSVWDAVRLEVGVPDSCPVVLHSF TQLDPDLPRPESSTQEIGEE LINGVIYSISLRKVQLHHGGNKGQR WLGYENESALNLYETCKVRTVKAGT LEKLVEHLVPAFQGSDLSYV TIFLCTYRAFTTTQQVLDLLFKRYG RCDALTASSRYGCILPYSDEDGGPQ DQLKNAISSILGTWLDQYSE DFCQPPDFPCLKQLVAYVQLNMPGS DLERRAHLLLAQLEHSEPIEAEPEA LSPVPALKPTPELELALTPA RAPSPVPAPAPEPEPAPTPAPGSEL EVAPAPAPELQQAPEPAVGLESAPA PALELEPAPEQDPAPSQTLE LEPAPAPVPSLQPSWPSPVVAENGL SEEKPHLLVFPPDLVAEQFTLMDAE LFKKVVPYHCLGSIWSQRDK KGKEHLAPTIRATVTQFNSVANCVI TTCLGNRSTKAPDRARVVEHWIEVA RECRILKNFSSLYAILSALQ SNSIHRLKKTWEDVSRDSFRIFQKL SEIFSDENNYSLSRELLIKEGTSKF ATLEMNPKRAQKRPKETGII QGTVPYLGTFLTDLVMLDTAMKDYL YGRLINFEKRRKEFEVIAQIKLLQS ACNNYSIAPDEQFGAWFRAV ERLSETESYNLSCELEPPSESASNT LRTKKNTAIVKRWSDRQAPSTELST SGSSHSKSCDQLRCGPYLSS GDIADALSVHSAGSSSSDVEEINIS FVPESPDGQEKKFWESASQSSPETS GISSASSSTSSSSASTTPVA ATRTHKRSVSGLCNSSSALPLYNQQ VGDCCIIRVSLDVDNGNMYKSILVT SQDKAPAVIRKAMDKHNLEE EEPEDYELLQILSDDRKLKIPENAN VFYAMNSTANYDFVLKKRTFTKGVK VKHGASSTLPRMKQKGLKIA
  KGIFTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Colorectal cancer, Pancreatic cancer, Pathways in cancer

Gene Information

• Gene Name: RALGDS ral guanine nucleotide dissociation stimulator [ Homo sapiens (human) ]
• Official Symbol: RALGDS
• Synonyms: RGF; RGDS; RalGEF
• Gene ID: 5900
• mRNA Refseq: NM_006266.4
• Protein Refseq: NP_006257.1
• MIM: 601619
• UniProt ID: Q12967