Recombinant Full Length Human RNASEH2C Protein, GST-tagged

• Cat.No.: RNASEH2C-1473HF
• Product Overview: Human AYP1 full-length ORF ( NP_115569.2, 1 a.a. - 164 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 164 amino acids
• Description: This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008]
• Molecular Mass: 44.2 kDa
• AA Sequence: MESGDEAAIE RHRVHLRSAT LRDAVPATLH LLPCEVAVDG PAPVGRFFTP AIRQGPEGLE VSFRGRCLRG EEVAVPPGLV GYVMVTEEKK VSMGKPDPLR DSGTDDQEEE PLERDFDRFI GATANFSRFT LWGLETIPGP DAKVRGALTW PSLAAAIHAQ VPED
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RNASEH2C ribonuclease H2, subunit C [ Homo sapiens ]
• Official Symbol: RNASEH2C
• Synonyms: RNASEH2C; ribonuclease H2, subunit C; ribonuclease H2 subunit C; AGS3; Aicardi Goutieres syndrome 3; AYP1; RNase H2 subunit C; RNase H1 small subunit; ribonuclease HI subunit C; aicardi-Goutieres syndrome 3 protein; FLJ20974; MGC22934
• Gene ID: 84153
• mRNA Refseq: NM_032193
• Protein Refseq: NP_115569
• MIM: 610330
• UniProt ID: Q8TDP1