Recombinant Full Length Human SEC31A Protein, C-Flag-tagged
Cat.No. : | SEC31A-1880HFL |
Product Overview : | Recombinant Full Length Human SEC31A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 131.4 kDa |
AA Sequence : | MKLKEVDRTAMQAWSPAQNHPIYLA TGTSAQQLDATFSTNASLEIFELDL SDPSLDMKSCATFSSSHRYH KLIWGPYKMDSKGDVSGVLIAGGEN GNIILYDPSKIIAGDKEVVIAQNDK HTGPVRALDVNIFQTNLVAS GANESEIYIWDLNNFATPMTPGAKT QPPEDISCIAWNRQVQHILASASPS GRATVWDLRKNEPIIKVSDH SNRMHCSGLAWHPDVATQMVLASED DRLPVIQMWDLRFASSPLRVLENHA RGILAIAWSMADPELLLSCG KDAKILCSNPNTGEVLYELPTNTQW CFDIQWCPRNPAVLSAASFDGRISV YSIMGGSTDGLRQKQVDKLS SSFGNLDPFGTGQPLPPLQIPQQTA QHSIVLPLKKPPKWIRRPVGASFSF GGKLVTFENVRMPSHQGAEQ QQQQHHVFISQVVTEKEFLSRSDQL QQAVQSQGFINYCQKKIDASQTEFE KNVWSFLKVNFEDDSRGKYL ELLGYRKEDLGKKIALALNKVDGAN VALKDSDQVAQSDGEESPAAEEQLL GEHIKEEKEESEFLPSSGGT FNISVSGDIDGLITQALLTGNFESA VDLCLHDNRMADAIILAIAGGQELL ARTQKKYFAKSQSKITRLIT AVVMKNWKEIVESCDLKNWREALAA VLTYAKPDEFSALCDLLGTRLENEG DSLLQTQACLCYICAGNVEK LVACWTKAQDGSHPLSLQDLIEKVV ILRKAVQLTQAMDTSTVGVLLAAKM SQYANLLAAQGSIAAALAFL PDNTNQPNIMQLRDRLCRAQGEPVA GHESPKIPYEKQQLPKGRPGPVAGH HQMPRVQTQQYYPHGENPPP PGFIMHGNVNPNAAGQLPTSPGHMH TQVPPYPQPQPYQPAQPYPFGTGGS AMYRPQQPVAPPTSNAYPNT PYISSASSYTGQSQLYAAQHQASSP TSSPATSFPPPPSSGASFQHGGPGA PPSSSAYALPPGTTGPQNGW NDPPALNRVPKKKKMPENFMPPVPI TSPIMNPLGDPQSQMLQQQPSAPVP LSSQSSFPQPHLPGGQPFHG VQQPLGQTGMPPSFSKPNIEGAPGA PIGNTFQHVQSLPTKKITKKPIPDE HLILKTTFEDLIQRCLSSAT DPQTKRKLDDASKRLEFLYDKLREQ TLSPTITSGLHNIARSIETRNYSEG LTMHTHIVSTSNFSETSAFM PVLKVVLTQANKLGV TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | SEC31A SEC31 homolog A, COPII coat complex component [ Homo sapiens (human) ] |
Official Symbol : | SEC31A |
Synonyms : | HPBKS; ABP125; ABP130; HSPC275; HSPC334; NEDSOSB; SEC31L1 |
Gene ID : | 22872 |
mRNA Refseq : | NM_001077208.4 |
Protein Refseq : | NP_001070676.1 |
MIM : | 610257 |
UniProt ID : | O94979 |
Products Types
◆ Recombinant Protein | ||
SEC31A-001H | Recombinant Human SEC31A Protein, His-tagged | +Inquiry |
SEC31A-7989M | Recombinant Mouse SEC31A Protein, His (Fc)-Avi-tagged | +Inquiry |
SEC31A-1966H | Recombinant Human SEC31A Protein, His (Fc)-Avi-tagged | +Inquiry |
Sec31a-5750M | Recombinant Mouse Sec31a Protein, Myc/DDK-tagged | +Inquiry |
SEC31A-4961R | Recombinant Rat SEC31A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SEC31A-581HCL | Recombinant Human SEC31A lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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