Description : |
The protein encoded by this gene is a transcription factor that can bind to the GC promoter region of a variety of genes, including those of the photoreceptor signal transduction system. The encoded protein binds to the same sites in promoter CpG islands as does the transcription factor SP1, although its expression is much more restricted compared to that of SP1. This gene may be involved in bipolar disorder and schizophrenia. |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Molecular Mass : |
112.7 kDa |
Protein Length : |
784 amino acids |
AA Sequence : |
MSDQKKEEEEEAAAAAAMATEGGKT SEPENNNKKPKTSGSQDSQPSPLAL LAATCSKIGTPGENQATGQQQIIID PSQGLVQLQNQPQQLELVTTQLAGN AWQLVASTPPASKENNVSQPASSSS SSSSSNNGSASPTKTKSGNSSTPGQ FQVIQVQNPSGSVQYQVIPQLQTVE GQQIQINPTSSSSLQDLQGQIQLIS AGNNQAILTAANRTASGNILAQNLA NQTVPVQIRPGVSIPLQLQTLPGTQ AQVVTTLPINIGGVTLALPVINNVA AGGGTGQVGQPAATADSGTSNGNQL VSTPTNTTTSASTMPESPSSSTTCT TTASTSLTSSDTLVSSADTGQYAST SASSSERTIEESQTPAATESEAQSS SQLQPNGMQNAQDQSNSLQQVQIVG QPILQQIQIQQPQQQIIQAIPPQSF QLQSGQTIQTIQQQPLQNVQLQAVN PTQVLIRAPTLTPSGQISWQTVQVQ NIQSLSNLQVQNAGLSQQLTITPVS SSGGTTLAQIAPVAVAGAPITLNTA QLASVPNLQTVSVANLGAAGVQVQG VPVTITSVAGQQQGQDGVKVQQATI APVTVAVGGIANATIGAVSPDQLTQ VHLQQGQQTSDQEVQPGKRLRRVAC SCPNCREGEGRGSNEPGKKKQHICH IEGCGKVYGKTSHLRAHLRWHTGER PFICNWMFCGKRFTRSDELQRHRRT HTGEKRFECPECSKRFMRSDHLSKH VKTHQNKKGGGTALAIVTSGELDSS VTEVLGSPRIVTVAAISQDSNPATP NVSTNMEEF |
Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |