Recombinant Full Length Human STING1 Protein, C-Flag-tagged
Cat.No. : | STING1-08HFL |
Product Overview : | Recombinant Full Length Human STING1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 42 kDa |
AA Sequence : | MPHSSLHPSIPCPRGHGAQKAALVL LSACLVTLWGLGEPPEHTLRYLVLH LASLQLGLLLNGVCSLAEEL RHIHSRYRGSYWRTVRACLGCPLRR GALLLLSIYFYYSLPNAVGPPFTWM LALLGLSQALNILLGLKGLA PAEISAVCEKGNFNVAHGLAWSYYI GYLRLILPELQARIRTYNQHYNNLL RGAVSQRLYILLPLDCGVPD NLSMADPNIRFLDKLPQQTGDHAGI KDRVYSNSIYELLENGQRAGTCVLE YATPLQTLFAMSQYSQAGFS REDRLEQAKLFCRTLEDILADAPES QNNCRLIAYQEPADDSSFSLSQEVL RHLRQEEKEEVTVGSLKTSA VPSTSTMSQEPELLISGMEKPLPLR TDFSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway |
Gene Name : | STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ] |
Official Symbol : | STING1 |
Synonyms : | ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta; TMEM173 |
Gene ID : | 340061 |
mRNA Refseq : | NM_198282.4 |
Protein Refseq : | NP_938023.1 |
MIM : | 612374 |
UniProt ID : | Q86WV6 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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