Recombinant Full Length Human SUMF2 Protein, GST-tagged

• Cat.No.: SUMF2-608HF
• Product Overview: Recombinant full length Human SUMF2 fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 36.74 kDa
• Protein Length: 301 amino acids
• AA Sequence: QATSMVQLQG GRFLMGTNSP DSRDGEGPVR EATVKPFAID IFPVTNKDFR DFVREKKYRT EAEMFGWSFV FEDFVSDELR NKATQPMKSV LWWLPVEKAF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: SUMF2 sulfatase modifying factor 2 [ Homo sapiens ]
• Official Symbol: SUMF2
• Synonyms: SUMF2; sulfatase modifying factor 2; sulfatase-modifying factor 2; DKFZp566I1024; C-alpha-formyglycine-generating enzyme 2; C-alpha-formylglycine-generating enzyme 2; paralog of the formylglycine-generating enzyme; pFGE; MGC99485; DKFZp686I1024; DKFZp781L1035; DKFZp686L17160
• Gene ID: 25870
• mRNA Refseq: NM_015411
• Protein Refseq: NP_056226
• MIM: 607940
• UniProt ID: Q8NBJ7