Recombinant Full Length Human SYNCRIP Protein, C-Flag-tagged

• Cat.No.: SYNCRIP-1889HFL
• Product Overview: Recombinant Full Length Human SYNCRIP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 69.4 kDa
• AA Sequence: MATEHVNGNGTEEPMDTTSAVIHSE NFQTLLDAGLPQKVAEKLDEIYVAG LVAHSDLDERAIEALKEFNE DGALAVLQQFKDSDLSHVQNKSAFL CGVMKTYRQREKQGTKVADSSKGPD EAKIKALLERTGYTLDVTTG QRKYGGPPPDSVYSGQQPSVGTEIF VGKIPRDLFEDELVPLFEKAGPIWD LRLMMDPLTGLNRGYAFVTF CTKEAAQEAVKLYNNHEIRSGKHIG VCISVANNRLFVGSIPKSKTKEQIL EEFSKVTEGLTDVILYHQPD DKKKNRGFCFLEYEDHKTAAQARRR LMSGKVKVWGNVGTVEWADPIEDPD PEVMAKVKVLFVRNLANTVT EEILEKAFSQFGKLERVKKLKDYAF IHFDERDGAVKAMEEMNGKDLEGEN IEIVFAKPPDQKRKERKAQR QAAKNQMYDDYYYYGPPHMPPPTRG RGRGGRGGYGYPPDYYGYEDYYDYY GYDYHNYRGGYEDPYYGYED FQVGARGRGGRGARGAAPSRGRGAA PPRGRAGYSQRGGPGSARGVRGARG GAQQQRGRGVRGARGGRGGN VGGKRKADGYNQPDSKRRQTNNQNW GSQPIAQQPLQGGDHSGNYGYKSEN QEFYQDTFGQQWK SGPTRTRRLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Stem cell - Pluripotency

Gene Information

• Gene Name: SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein [ Homo sapiens (human) ]
• Official Symbol: SYNCRIP
• Synonyms: PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q
• Gene ID: 10492
• mRNA Refseq: NM_006372.5
• Protein Refseq: NP_006363.4
• MIM: 616686
• UniProt ID: O60506