Recombinant Full Length Human TFRC Protein, C-Flag-tagged

• Cat.No.: TFRC-466HFL
• Product Overview: Recombinant Full Length Human TFRC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 84.7 kDa
• AA Sequence: MMDQARSAFSNLFGGEPLSYTRFSL ARQVDGDNSHVEMKLAVDEEENADN NTKANVTKPKRCSGSICYGT IAVIVFFLIGFMIGYLGYCKGVEPK TECERLAGTESPVREEPGEDFPAAR RLYWDDLKRKLSEKLDSTDF TGTIKLLNENSYVPREAGSQKDENL ALYVENQFREFKLSKVWRDQHFVKI QVKDSAQNSVIIVDKNGRLV YLVENPGGYVAYSKAATVTGKLVHA NFGTKKDFEDLYTPVNGSIVIVRAG KITFAEKVANAESLNAIGVL IYMDQTKFPIVNAELSFFGHAHLGT GDPYTPGFPSFNHTQFPPSRSSGLP NIPVQTISRAAAEKLFGNME GDCPSDWKTDSTCRMVTSESKNVKL TVSNVLKEIKILNIFGVIKGFVEPD HYVVVGAQRDAWGPGAAKSG VGTALLLKLAQMFSDMVLKDGFQPS RSIIFASWSAGDFGSVGATEWLEGY LSSLHLKAFTYINLDKAVLG TSNFKVSASPLLYTLIEKTMQNVKH PVTGQFLYQDSNWASKVEKLTLDNA AFPFLAYSGIPAVSFCFCED TDYPYLGTTMDTYKELIERIPELNK VARAAAEVAGQFVIKLTHDVELNLD YERYNSQLLSFVRDLNQYRA DIKEMGLSLQWLYSARGDFFRATSR LTTDFGNAEKTDRFVMKKLNDRVMR VEYHFLSPYVSPKESPFRHV
  FWGSGSHTLPALLENLKLRKQNNGA FNETLFRNQLALATWTIQGAANALS GDVWDIDNEFTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage

Gene Information

• Gene Name: TFRC transferrin receptor [ Homo sapiens (human) ]
• Official Symbol: TFRC
• Synonyms: T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
• Gene ID: 7037
• mRNA Refseq: NM_001128148.3
• Protein Refseq: NP_001121620.1
• MIM: 190010
• UniProt ID: P02786