Recombinant Full Length Human TGM5 Protein, C-Flag-tagged

• Cat.No.: TGM5-1869HFL
• Product Overview: Recombinant Full Length Human TGM5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.6 kDa
• AA Sequence: MAQGLEVALTDLQSSRNNVRHHTEE ITVDHLLVRRGQAFNLTLYFRNRSF QPGLDNIIFVVETGPLPDLA LGTRAVFSLARHHSPSPWIAWLETN GATSTEVSLCAPPKAAVGRYLLKIH IDSFQGSVTAYQLGEFILLF NPWCPEDAVYLDSEPQRQEYVMNDY GFIYQGSKNWIRPCPWNYGQFEDKI IDICLKLLDKSLHFQTDPAT DCALRGSPVYVSRVVCAMINSNDDN GVLNGNWSENYTDGANPAEWTGSVA ILKQWNATGCQPVRYGQCWV FAAVMCTVMRCLGIPTRVITNFDSG HDTDGNLIIDEYYDNTGRILGNKKK DTIWNFHVWNECWMARKDLP PAYGGWQVLDATPQEMSNGVYCCGP ASVRAIKEGEVDLNYDTPFVFSMVN ADCMSWLVQGGKEQKLHQDT SSVGNFISTKSIQSDERDDITENYK YEEGSLQERQVFLKALQKLKARSFH GSQRGAELQPSRPTSLSQDS PRSLHTPSLRPSDVVQVSLKFKLLD PPNMGQDICFVLLALNMSSQFKDLK VNLSAQSLLHDGSPLSPFWQ DTAFITLSPKEAKTYPCKISYSQYS QYLSTDKLIRISALGEEKSSPEKIL VNKIITLSYPSITINVLGAA VVNQPLSIQVIFSNPLSEQVEDCVL TVEGSGLFKKQQKVFLGVLKPQHQA SIILETVPFKSGQRQIQANM RSNKFKDIKGYRNVYVDFAL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: TGM5 transglutaminase 5 [ Homo sapiens (human) ]
• Official Symbol: TGM5
• Synonyms: TGX; PSS2; TGM6; TGMX; TG(X); TGASE5; TGASEX
• Gene ID: 9333
• mRNA Refseq: NM_201631.4
• Protein Refseq: NP_963925.2
• MIM: 603805
• UniProt ID: O43548