Species : |
Human |
Source : |
In Vitro Cell Free System |
Tag : |
GST |
Protein Length : |
33-207 amino acids |
Description : |
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimers disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
44.88 kDa |
AA Sequence : |
WGAVATSAGG EESLKCEDLK VGQYICKDPK INDATQEPVN CTNYTAHVSC FPAPNITCKD SSGNETHFTG NEVGFFKPIS CRNVNGYSYK VAVALSLFLG WLGADRFYLG YPALGLLKFC TVGFCGIGSL IDFILISMQI VGPSDGSSYI IDYYGTRLTR LSITNETFRK TQLYP |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |