Recombinant Full Length Human TNIP1 Protein, C-Flag-tagged

• Cat.No.: TNIP1-2151HFL
• Product Overview: Recombinant Full Length Human TNIP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 71.7 kDa
• AA Sequence: MEGRGPYRIYDPGGSVPSGEASAAF ERLVKENSRLKEKMQGIKMLGELLE ESQMEATRLRQKAEELVKDN ELLPPPSPSLGSFDPLAELTGKDSN VTASPTAPACPSDKPAPVQKPPSSG TSSEFEVVTPEEQNSPESSS HANAMALDPLPREDGNLMLHLQRLE TTLSVCAEEPDHGQLFTHLGRMALE FNRLASKVHKNEQRTSILQT LCEQLRKENEALKAKLDKGLEQRDQ AAERLREENLELKKLLMSNGNKEGA SGRPGSPKMEGTGKKAVAGQ QQASVTAGKVPEVVALGAAEKKVKM LEQQRSELLEVNKQWDQHFRSMKQQ YEQKITELRQKLADLQKQVT DLEAEREQKQRDFDRKLLLAKSKIE MEETDKEQLTAEAKELRQKVKYLQD QLSPLTRQREYQEKEIQRLN KALEEALSIQTPPSSPPTAFGSPEG AGALLRKQELVTQNELLKQQVKIFE EDFQRERSDRERMNEEKEEL KKQVEKLQAQVTLSNAQLKAFKDEE KAREALRQQKRKAKASGERYHVEPH PEHLCGAYPYAYPPMPAMVP HHGFEDWSQIRYPPPPMAMEHPPPL PNSRLFHLPEYTWRLPCGGVRNPNQ SSQVMDPPTARPTEPESPKN DREGPQ TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: TNIP1 TNFAIP3 interacting protein 1 [ Homo sapiens (human) ]
• Official Symbol: TNIP1
• Synonyms: VAN; NAF1; ABIN-1; nip40-1
• Gene ID: 10318
• mRNA Refseq: NM_006058.5
• Protein Refseq: NP_006049.3
• MIM: 607714
• UniProt ID: Q15025