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Recombinant Human AAPLN protein, GST-tagged

Cat.No. : AAPLN-505H
Product Overview : Human AAPLN full-length ORF (AAH21104.1, 1 a.a. ~ 122 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 39.16 kDa
AA Sequence : MSATWCSPEGQGMGQGPGREVGGNS AASGPASPIRDPCLSEAGLKGPPSA HPRRLCLLHRLVCFSGGLTSIQLSP RTCCSHQWAQLFSPACFPQWRAPGC SLDDSRSLTRIRPVHLPGPSLD
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : APLN apelin [ Homo sapiens ]
Official Symbol : APLN
Synonyms : APLN; apelin; APEL; XNPEP2; AGTRL1 ligand; APJ endogenous ligand; apelin
Gene ID : 8862
mRNA Refseq : NM_017413
Protein Refseq : NP_059109
MIM : 300297
UniProt ID : Q9ULZ1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Does the study of APLN involve genetic engineering technology? 12/06/2022

Yes, genetic engineering techniques are often used to produce APLN s.

Does APLN interact with other drugs? 09/27/2022

There may be interactions, and it is recommended to avoid concurrent use of other drugs during use, especially those that affect the cardiovascular system.

What is the action mechanism of APLN ? 05/25/2022

APLN promotes cardiovascular protection and anti-tumor effects by binding to APJ receptors.

In what diseases might APLN have potential applications? 04/15/2022

APLN has potential applications in the treatment of cardiovascular diseases, tumors and metabolic diseases.

In what way can APLN be administered? 05/07/2021

APLN can be administered intravenously or subcutaneously.

What is the dose of APLN to treat cardiovascular disease? 02/19/2021

Dosage should be determined according to the specific situation, it is recommended to consult with a professional doctor.

Does the development of APLN involve animal experiments? 05/03/2020

In the development process, it usually goes through a series of animal experiments to verify its effectiveness and safety.

What are the side effects of APLN ? 02/17/2020

Common side effects include injection site pain, fever, nausea, etc., but most patients tolerate them well.

What is the protective effect of APLN on cardiovascular diseases? 01/15/2020

APLN can promote blood vessel dilation, inhibit inflammatory response, and facilitate the survival and repair of cardiomyocytes.

Has the application of APLN in tumor therapy been clinically verified? 01/18/2019

There are currently no large-scale clinical trials to confirm its use in cancer treatment, but preliminary research results are promising.

Customer Reviews (3)

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Reviews
12/16/2022

    Western blot experiments using this protein can obtain clearly distinguishable bands, indicating that it has high clarity and legibility.

    02/10/2022

      In the course of repeated experiments, the stability of this protein has remained consistent, which provides us with great convenience.

      12/12/2019

        I appreciate the manufacturer's pursuit of product quality, and their product repeatability is very good, which makes me more confident in the experimental results.

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