Recombinant Human AATF Protein, GST-tagged

• Cat.No.: AATF-027H
• Product Overview: Human AATF full-length ORF ( NP_036270.1, 1 a.a. - 560 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 89.5 kDa
• AA Sequence: MAGPQPLALQLEQLLNPRPSEADPE ADPEEATAARVIDRFDEGEDGEGDF LVVGSIRKLASASLLDTDKRYCGKT TSRKAWNEDHWEQTLPGSSDEEISD EEGSGDEDSEGLGLEEYDEDDLGAA EEQECGDHRESKKSRSHSAKTPGFS VQSISDFEKFTKGMDDLGSSEEEED EESGMEEGDDAEDSQGESEEDRAGD RNSEDDGVVMTFSSVKVSEEVEKGR AVKNQIALWDQLLEGRIKLQKALLT TNQLPQPDVFPLFKDKGGPEFSSAL KNSHKALKALLRSLVGLQEELLFQY PDTRYLVDGTKPNAGSEEISSEDDE LVEEKKQQRRRVPAKRKLEMEDYPS FMAKRFADFTVYRNRTLQKWHDKTK LASGKLGKGFGAFERSILTQIDHIL MDKERLLRRTQTKRSVYRVLGKPEP AAQPVPESLPGEPEILPQAPANAHL KDLDEEIFDDDDFYHQLLRELIERK TSSLDPNDQVAMGRQWLAIQKLRSK IHKKVDRKASKGRKLRFHVLSKLLS FMAPIDHTTMNDDARTELYRSLFGQ LHPPDEGHGD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AATF apoptosis antagonizing transcription factor [ Homo sapiens ]
• Official Symbol: AATF
• Synonyms: AATF; apoptosis antagonizing transcription factor; protein AATF; CHE 1; CHE1; DED; rb-binding protein Che-1; apoptosis-antagonizing transcription factor; CHE-1
• Gene ID: 26574
• mRNA Refseq: NM_012138
• Protein Refseq: NP_036270
• MIM: 608463
• UniProt ID: Q9NY61