Recombinant Human ACADM Protein, GST-Tagged

• Cat.No.: ACADM-134H
• Product Overview: Human ACADM partial ORF ( NP_000007, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.05 kDa
• AA Sequence: MAARLLRGSLRVLGGHRAPRQLPAA RCSHSGGEERLETPSAKKLTDIGIR RIFSPEHDIFRKSVRKFFQEEVIPH HSEWEKAGEVSREVWEKAGKQGLLG VNIAEHLGGIGGDLYSAAIVWEEQA YSNCSGPGFSIHSGIVMSYITNHGS EEQIKHFIPQMTAGKCIGAIAMTEP GAGSDLQGIKTNAKKDGSDWILNGS KVFISNGSLSDVVIVVAVTNHEAPS PAHGISLFLVENGMKGFIKGRKLHK MGLKAQDTAELFFEDIRLPASALLG EENKGFYYIMKELPQERLLIADVAI SASEFMFEETRNYVKQRKAFGKTVA HLQTVQHKLAELKTHICVTRAFVDN CLQLHEAKRLDSATACMAKYWASEL QNSVAYDCVQLHGGWGYMWEYPIAK AYVDARVQPIYGGTNEIMKELIARE IVFDK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain [ Homo sapiens ]
• Official Symbol: ACADM
• Synonyms: ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl Coenzyme A dehydrogenase, C 4 to C 12 straight chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD1; MCAD; MCADH; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
• Gene ID: 34
• mRNA Refseq: NM_000016
• Protein Refseq: NP_000007
• MIM: 607008
• UniProt ID: P11310