Recombinant Human ACADSB Protein, GST-Tagged
Cat.No. : | ACADSB-137H |
Product Overview : | Human ACADSB full-length ORF ( AAH13756.1, 1 a.a. - 432 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 95.5 kDa |
AA Sequence : | MSGCGLFLRTTAAARACRGLVVSTA NRRLLRTSPPVRAFAKELFLGKIKK KEVFPFPEVSQDELNEINQFLGPVE KFFTEEVDSRKIDQEGKIPDETLEK LKSLGLFGLQVPEEYGGLGFSNTMY SRLGEIISMDGSITVTLAAHQAIGL KGIILAGTEEQKAKYLPKLASGEHI AAFCLTEPASGSDAASIRSRATLSE DKKHYILNGSKVWITNGGLANIFTV FAKTEVVDSDGSVKDKITAFIVERD FGGVTNGKPEDKLGIRGSNTCEVHF ENTKIPVENILGEVGDGFKVAMNIL NSGRFSMGSVVAGLLKRLIEMTAEY ACTRKQFNKRLSEFGLIQEKFALMA QKAYVMESMTYLTAGMLDQPGFPDC SIEAAMVKVFSSEAAWQCVSEALQI LGGLGYTRDYPYERILRDTRILLIF EGTNEILRMYIALTGLQHAGRILTT RIHELKQAKVSTVMDTVGRRLRDSL GRTVDLGLTGNHGVVHPSLADSANK FEENTYCFGRTVETLLLRFGKTIME EQLVLKRVANILINLYGMTAVLSRA SRSIRIGLRNHDHEVLLANTFCVEA YLQNLFSLSQLDKYAPENLDEQIKK VSQQILEKRAYICAHPLDRTC |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ACADSB acyl-CoA dehydrogenase, short/branched chain [ Homo sapiens ] |
Official Symbol : | ACADSB |
Synonyms : | ACADSB; acyl-CoA dehydrogenase, short/branched chain; ACAD7; SBCAD; 2-MEBCAD; short/branched chain specific acyl-CoA dehydrogenase, mitochondrial; 2-methylbutyryl-coenzyme A dehydrogenase; 2-methyl branched chain acyl-CoA dehydrogenase; 2 MEBCAD; 2 methyl branched chain acyl CoA dehydrogenase; 2 methylbutyryl CoA dehydrogenase; 2-methylbutyryl-CoA dehydrogenase; ACDSB_HUMAN; acyl CoA dehydrogenase, short/branched chain; OTTHUMP00000020685; OTTHUMP00000046795; Short/branched chain specific acyl-CoA dehydrogenase; acyl-Coenzyme A dehydrogenase, short/branched chain; 2-methylbutyryl-coenzyme A dehydrogenase; short/branched chain specific acyl-CoA dehydrogenase, mitochondrial; EC 1.3.99 |
Gene ID : | 36 |
mRNA Refseq : | NM_001609 |
Protein Refseq : | NP_001600 |
MIM : | 600301 |
UniProt ID : | P45954 |
Products Types
◆ Recombinant Protein | ||
Acadsb-25M | Recombinant Mouse Acadsb Protein, His-tagged | +Inquiry |
ACADSB-240M | Recombinant Mouse ACADSB Protein, His (Fc)-Avi-tagged | +Inquiry |
ACADSB-24H | Recombinant Human ACADSB Protein, His&GST-tagged | +Inquiry |
Acadsb-26R | Recombinant Rat Acadsb Protein, His-tagged | +Inquiry |
ACADSB-94R | Recombinant Rat ACADSB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACADSB-9112HCL | Recombinant Human ACADSB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe activity of acyl-CoA dehydrogenase short/branched chain contributes to the breakdown of branched-chain amino acids and fatty acids to produce energy in cells.
Acyl-CoA dehydrogenase short/branched chain protein is located in the mitochondrial matrix.
Acyl-CoA dehydrogenase short/branched chain protein has specificity for short/branched chain fatty acyl-CoA substrates.
Mutations in this protein are associated with a variety of metabolic disorders, including isovaleric acidemia and 2-methylbutyryl-CoA dehydrogenase deficiency.
There are currently no known inhibitors or activators of acyl-CoA dehydrogenase short/branched chain protein.
Acyl-CoA dehydrogenase short/branched chain plays a key role in energy metabolism and the catabolism of branched-chain amino acids in cells.
Acyl-CoA dehydrogenase short/branched chain protein has a flavin adenine dinucleotide (FAD)-binding domain that is essential for its function.
The expression of acyl-CoA dehydrogenase short/branched chain is regulated by a variety of factors, including gene expression and protein degradation pathways.
Research is ongoing to further understand the function and regulation of acyl-CoA dehydrogenase short/branched chain protein, as well as its role in metabolic disorders.
Acyl-CoA dehydrogenase short/branched chain protein is involved in the metabolism of branched-chain amino acids and fatty acids.
Customer Reviews (2)
Write a reviewHighly effective in detecting and measuring the activity of esterases in esterase assays.
Demonstrates excellent specificity and sensitivity in detecting the target protein in fluorescence-based assays.
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