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Recombinant Human ACKR2 Protein, GST-Tagged

Cat.No. : ACKR2-0496H
Product Overview : Human ACKR2 full-length ORF (AAH08816, 1 a.a. - 384 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 67.98 kDa
AA Sequence : MAATASPQPLATEDADSENSSFYYY DYLDEVAFMLCRKDAVVSFGKVFLP VFYSLIFVLGLSGNLLLLMVLLRYV PRRRMVEIYLLNLAISNLLFLVTLP FWGISVAWHWVFGSFLCKMVSTLYT INFYSGIFFISCMSLDKYLEIVHAQ PYHRLRTRAKSLLLATIVWAVSLAV SIPDMVFVQTHENPKGVWNCHADFG GHGTIWKLFLRFQQNLLGFLLPLLA MIFFYSRIGCVLVRLRPAGQGRALK IAAALVVAFFVLWFPYNLTLFLHTL LDLQVFGNCEVSQHLDYALQVTESI AFLHCCFSPILYAFSSHRFRQYLKA FLAAVLGWHLAPGTAQASLSSCSES SILTAQEEMTGMNDLGERQSENYPN KEDVGNKSA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ACKR2 atypical chemokine receptor 2 [ Homo sapiens (human) ]
Official Symbol : ACKR2
Synonyms : ACKR2; atypical chemokine receptor 2; CCBP2; chemokine binding protein 2; CMKBR9; chemokine-binding protein 2; CCR9; CCR10; D6; chemokine receptor D6; chemokine receptor CCR-9; C-C chemokine receptor D6; chemokine receptor CCR-10; chemokine (C-C) receptor 9; chemokine-binding protein D6; chemokine (C-C motif) receptor 9; CC-chemokine-binding receptor JAB61; hD6; MGC126678; MGC138250;
Gene ID : 1238
mRNA Refseq : NM_001296
Protein Refseq : NP_001287
MIM : 602648
UniProt ID : O00590

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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