Recombinant Human ACO2 Protein, GST-Tagged

• Cat.No.: ACO2-165H
• Product Overview: Human ACO2 full-length ORF ( NP_001089.1, 1 a.a. - 780 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 111.8 kDa
• AA Sequence: MAPYSLLVTRLQKALGVRQYHVASV LCQRAKVAMSHFEPNEYIHYDLLEK NINIVRKRLNRPLTLSEKIVYGHLD DPASQEIERGKSYLRLRPDRVAMQD ATAQMAMLQFISSGLSKVAVPSTIH CDHLIEAQVGGEKDLRRAKDINQEV YNFLATAGAKYGVGFWKPGSGIIHQ IILENYAYPGVLLIGTDSHTPNGGG LGGICIGVGGADAVDVMAGIPWELK CPKVIGVKLTGSLSGWSSPKDVILK VAGILTVKGGTGAIVEYHGPGVDSI SCTGMATICNMGAEIGATTSVFPYN HRMKKYLSKTGREDIANLADEFKDH LVPDPGCHYDQLIEINLSELKPHIN GPFTPDLAHPVAEVGKVAEKEGWPL DIRVGLIGSCTNSSYEDMGRSAAVA KQALAHGLKCKSQFTITPGSEQIRA TIERDGYAQILRDLGGIVLANACGP CIGQWDRKDIKKGEKNTIVTSYNRN FTGRNDANPETHAFVTSPEIVTALA IAGTLKFNPETDYLTGTDGKKFRLE APDADELPKGEFDPGQDTYQHPPKD SSGQHVDVSPTSQRLQLLEPFDKWD GKDLEDLQILIKVKGKCTTDHISAA GPWLKFRGHLDNISNNLLIGAINIE NGKANSVRNAVTQEFGPVPDTARYY KKHGIRWVVIGDENYGEGSSREHAA LEPRHLGGRAIITKSFARIHETNLK KQGLLPLTFADPADYNKIHPVDKLT IQGLKDFTPGKPLKCIIKHPNGTQE TILLNHTFNETQIEWFRAGSALNRM KELQQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACO2 aconitase 2, mitochondrial [ Homo sapiens ]
• Official Symbol: ACO2
• Synonyms: ACO2; aconitase 2, mitochondrial; aconitate hydratase, mitochondrial; ACONM; citrate hydro-lyase; ICRD; MGC20605; MGC33908
• Gene ID: 50
• mRNA Refseq: NM_001098
• Protein Refseq: NP_001089
• MIM: 100850
• UniProt ID: Q99798