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Recombinant Human ACSF2 protein, GST-tagged

Cat.No. : ACSF2-194H
Product Overview : Recombinant Human ACSF2 protein(NP_079425)(336-615 aa), fused with GST tag, was expressed in E. coli.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.). 5 % trehalose and 5 % mannitol are added as protectants before lyophilization.
Protein length : 336-615 aa
AA Sequence : FNGKKALEAISRERGTFLYGTPTMF VDILNQPDFSSYDISTMCGGVIAGS PAPPELIRAIINKINMKDLVVAYGT TENSPVTFAHFPEDTVEQKAESVGR IMPHTEARIMNMEAGTLAKLNTPGE LCIRGYCVMLGYWGEPQKTEEAVDQ DKWYWTGDVATMNEQGFCKIVGRSK DMIIRGGENIYPAELEDFFHTHPKV QEVQVVGVKDDRMGEEICACIRLKD GEETTVEEIKAFCKGKISHFKIPKY IVFVTNYPLTISGKIQKFKLREQME RHLNL
Purity : 85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : ACSF2 acyl-CoA synthetase family member 2 [ Homo sapiens ]
Official Symbol : ACSF2
Synonyms : ACSF2; acyl-CoA synthetase family member 2; acyl-CoA synthetase family member 2, mitochondrial; ACSMW; FLJ20920; PPARG binding, long chain fatty acid acyl Co-A ligase like; AVYV493;
Gene ID : 80221
mRNA Refseq : NM_025149
Protein Refseq : NP_079425
MIM : 610465
UniProt ID : Q96CM8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Are there any therapeutic implications of targeting ACSF2? 11/16/2022

ACSF2 inhibitors have been proposed as a potential therapeutic strategy for the treatment of metabolic disorders, although further research is needed to validate this approach.

What is the substrate specificity of ACSF2? 07/11/2022

ACSF2 has a broad substrate specificity and can activate a range of long-chain fatty acids including palmitic acid, oleic acid, and arachidonic acid.

What is the mechanism of ACSF2-mediated fatty acid activation? 03/19/2022

ACSF2 activates fatty acids by converting them into their acyl-CoA derivatives through the use of ATP and CoA.

What is the role of ACSF2 in cellular stress response? 09/27/2021

ACSF2 has been shown to play a role in the cellular stress response by regulating the activation of AMPK and the expression of stress response genes.

What is the role of ACSF2 in cancer? 10/09/2020

ACSF2 has been shown to play a role in tumor growth and progression in several types of cancer, including colorectal cancer and hepatocellular carcinoma.

Where is ACSF2 primarily expressed? 09/17/2020

ACSF2 is highly expressed in the liver and also in other tissues such as the brain, heart, and muscle.

How does ACSF2 affect lipid droplet dynamics? 04/28/2020

ACSF2 has been shown to play a role in the regulation of lipid droplet dynamics by regulating the activity of lipases and promoting the formation of lipid droplets.

What is the effect of ACSF2 overexpression on fatty acid metabolism? 11/10/2019

Overexpression of ACSF2 has been shown to increase fatty acid oxidation and decrease fatty acid synthesis in hepatocytes.

How does ACSF2 affect insulin sensitivity? 06/11/2019

ACSF2 has been shown to play a role in insulin sensitivity by regulating glucose uptake and lipid metabolism in skeletal muscle cells.

How is ACSF2 involved in the regulation of inflammation? 11/19/2018

ACSF2 has been shown to regulate the production of inflammatory cytokines in macrophages and may play a role in the development of inflammatory diseases.

Customer Reviews (5)

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Reviews
10/07/2021

    Super fast shipping and excellent customer service. Will definitely buy from again.

    09/14/2021

      Great product! Really satisfied with the quality of the recombinant protein.

      07/13/2020

        Wonderful product!

        09/25/2018

          Overall, I highly recommend this recombinant protein and the manufacturer for their excellent product and service.

          08/21/2018

            I was impressed with the strict quality control measures the manufacturer had in place to ensure consistent quality.

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