Recombinant Human ACSL5 Protein (33-683 aa), His-tagged

• Cat.No.: ACSL5-1924H
• Product Overview: Recombinant Human ACSL5 Protein (33-683 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Description: Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 76.4 kDa
• Protein length: 33-683 aa
• AA Sequence: TRPQPVLPLLDLNNQSVGIEGGARK GVSQKNNDLTSCCFSDAKTMYEVFQ RGLAVSDNGPCLGYRKPNQPYRWLS YKQVSDRAEYLGSCLLHKGYKSSPD QFVGIFAQNRPEWIISELACYTYSM VAVPLYDTLGPEAIVHIVNKADIAM VICDTPQKALVLIGNVEKGFTPSLK VIILMDPFDDDLKQRGEKSGIEILS LYDAENLGKEHFRKPVPPSPEDLSV ICFTSGTTGDPKGAMITHQNIVSNA AAFLKCVEHAYEPTPDDVAISYLPL AHMFERIVQAVVYSCGARVGFFQGD IRLLADDMKTLKPTLFPAVPRLLNR IYDKVQNEAKTPLKKFLLKLAVSSK FKELQKGIIRHDSFWDKLIFAKIQD SLGGRVRVIVTGAAPMSTSVMTFFR AAMGCQVYEAYGQTECTGGCTFTLP GDWTSGHVGVPLACNYVKLEDVADM NYFTVNNEGEVCIKGTNVFKGYLKD PEKTQEALDSDGWLHTGDIGRWLPN GTLKIIDRKKNIFKLAQGEYIAPEK IENIYNRSQPVLQIFVHGESLRSSL VGVVVPDTDVLPSFAAKLGVKGSFE ELCQNQVVREAILEDLQKIGKESGL KTFEQVKAIFLHPEPFSIENGLLTP TLKAKRGELSKYFRTQIDSLYEHIQ D
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: ACSL5 acyl-CoA synthetase long-chain family member 5 [ Homo sapiens ]
• Official Symbol: ACSL5
• Synonyms: ACSL5; ACS2; ACS5; LACS 5; FACL5
• Gene ID: 51703
• mRNA Refseq: NM_016234
• Protein Refseq: NP_057318
• MIM: 605677
• UniProt ID: Q9ULC5