| Description : |
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
80.4 kDa |
| AA Sequence : |
MLTFFLVSGGSLWLFVEFVLSLLEK MQTQEILRILRLPELGDLGQFFRSL SATTLVSMGALAAILAYWFTHRPKA LQPPCNLLMQSEEVEDSGGARRSVI GSGPQLLTHYYDDARTMYQVFRRGL SISGNGPCLGFRKPKQPYQWLSYQE VADRAEFLGSGLLQHNCKACTDQFI GVFAQNRPEWIIVELACYTYSMVVV PLYDTLGPGAIRYIINTADISTVIV DKPQKAVLLLEHVERKETPGLKLII LMDPFEEALKERGQKCGVVIKSMQA VEDCGQENHQAPVPPQPDDLSIVCF TSGTTGNPKGAMLTHGNVVADFSGF LKVTEKVIFPRQDDVLISFLPLAHM FERVIQSVVYCHGGRVGFFQGDIRL LSDDMKALCPTIFPVVPRLLNRMYD KIFSQANTPLKRWLLEFAAKRKQAE VRSGIIRNDSIWDELFFNKIQASLG GCVRMIVTGAAPASPTVLGFLRAAL GCQVYEGYGQTECTAGCTFTTPGDW TSGHVGAPLPCNHIKLVDVEELNYW ACKGEGEICVRGPNVFKGYLKDPDR TKEALDSDGWLHTGDIGKWLPAGTL KIIDRKKHIFKLAQGEYVAPEKIEN IYIRSQPVAQIYVHGDSLKAFLVGI VVPDPEVMPSWAQKRGIEGTYADLC TNKDLKKAILEDMVRLGKESGLHSF EQVKAIHIHSDMFSVQNGLLTPTLK AKRPELREYFKKQIEELYSISMTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
