Recombinant Human ACSS2 Protein, GST-tagged

• Cat.No.: ACSS2-209H
• Product Overview: Human ACSS2 full-length ORF ( AAH98422.1, 1 a.a. - 606 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 94 kDa
• AA Sequence: MKGATTNICYNVLDRNVHEKKLGDK VAFYWEGNEPGETTQITYHQLLVQV CQFSNVLRKQGIQKGDRVAIYMPMI PELVVAMLACARIGALHSIVFAGFS SESLCERILDSSCSLLITTDAFYRG EKLVNLKELADEALQKCQEKGFPVR CCIVVKHLGRAELGMGDSTSQSPPI KRSCPDVQISWNQGIDLWWHELMQE AGDECEPEWCDAEDPLFILYTSGST GKPKGVVHTVGGYMLYVATTFKYVF DFHAEDVFWCTADIGWITGHSYVTY GPLANGATSVLFEGIPTYPDVNRLW SIVDKYKVTKFYTAPTAIRLLMKFG DEPVTKHSRASLQVLGTVGEPINPE AWLWYHRVVGAQRCPIVDTFWQTET GGHMLTPLPGATPMKPGSATFPFFG VAPAILNESGEELEGEAEGYLVFKQ PWPGIMRTVYGNHERFETTYFKKFP GYYVTGDGCQRDQDGYYWITGRIDD MLNVSGHLLSTAEVESALVEHEAVA EAAVVGHPHPVKGECLYCFVTLCDG HTFSPKLTEELKKQIREKIGPIATP DYIQNAPGLPKTRSGKIMRRVLRKI AQNDHDLGDMSTVADPSVISHLFSH RCLTIQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACSS2 acyl-CoA synthetase short-chain family member 2 [ Homo sapiens ]
• Official Symbol: ACSS2
• Synonyms: ACSS2; acyl-CoA synthetase short-chain family member 2; ACAS2, acetyl Coenzyme A synthetase 2 (ADP forming); acetyl-coenzyme A synthetase, cytoplasmic; AceCS; ACS; ACSA; dJ1161H23.1; acetate thiokinase; acetate-CoA ligase; acyl-activating enzyme; cytoplasmic acetyl-coenzyme A synthetase; acetyl-Coenzyme A synthetase 2 (ADP forming); ACAS2; ACECS; DKFZp762G026
• Gene ID: 55902
• mRNA Refseq: NM_001076552
• Protein Refseq: NP_001070020
• MIM: 605832
• UniProt ID: Q9NR19