Active Recombinant Human ACVR1B Protein, GST-tagged
Cat.No. : | ACVR1B-249H |
Product Overview : | Human ACVR1B (NP_004293.1, 150 a.a. - 505 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010] |
Source : | Insect Cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Bio-activity : | The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: TopoIIa peptide. ATP: 100 uM. |
Molecular Mass : | 68 kDa |
Purity : | 76 % by SDS-PAGE/CBB staining |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol) |
Gene Name : | ACVR1B activin A receptor, type IB [ Homo sapiens ] |
Official Symbol : | ACVR1B |
Synonyms : | ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB; |
Gene ID : | 91 |
mRNA Refseq : | NM_004302 |
Protein Refseq : | NP_004293 |
MIM : | 601300 |
UniProt ID : | P36896 |
Products Types
◆ Recombinant Protein | ||
ACVR1B-165H | Recombinant Human ACVR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR1B-148R | Recombinant Rat ACVR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
Acvr1b-288M | Recombinant Mouse Acvr1b Protein, His-tagged | +Inquiry |
ACVR1B-1289H | Recombinant Human ACVR1B Protein (N150-I505), His tagged | +Inquiry |
ACVR1B-082H | Recombinant Human ACVR1B Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
ACVR1B-1206RCL | Recombinant Rat ACVR1B cell lysate | +Inquiry |
ACVR1B-1356CCL | Recombinant Cynomolgus ACVR1B cell lysate | +Inquiry |
ACVR1B-2130HCL | Recombinant Human ACVR1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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