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Recombinant Human ADAM12 Protein, GST-tagged

Cat.No. : ADAM12-274H
Product Overview : Human ADAM12 full-length ORF ( AAH60804.1, 1 a.a. - 737 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 106.8 kDa
AA Sequence : MAARPLPVSPARALLLALAGALLAP CEARGVSLWNQGRADEVVSASVRSG DLWIPVKSFDSKNHPEVLNIRLQRE SKELIINLERNEGLIASSFTETHYL QDGTDVSLARNYTGHCYYHGHVRGY SDSAVSLSTCSGLRGLIVFENESYV LEPMKSATNRYKLFPAKKLKSVRGS CGSHHNTPNLAAKNVFPPPSQTWAR RHKRETLKATKYVELVIVADNREFQ RQGKDLEKVKQRLIEIANHVDKFYR PLNIRIVLVGVEVWNDMDKCSVSQD PFTSLHEFLDWRKMKLLPRKSHDNA QLVSGVYFQGTTIGMAPIMSMCTAD QSGGIVMDHSDNPLGAAVTLAHELG HNFGMNHDTLDRGCSCQMAVEKGGC IMNASTGYPFPMVFSSCSRKDLETS LEKGMGVCLFNLPEVRESFGGQKCG NRFVEEGEECDCGEPEECMNRCCNA TTCTLKPDAVCAHGLCCEDCQLKPA GTACRDSSNSCDLPEFCTGASPHCP ANVYLHDGHSCQDVDGYCYNGICQT HEQQCVTLWGPGAKPAPGICFERVN SAGDPYGNCGKVSKSSFAKCEMRDA KCGKIQCQGGASRPVIGTNAVSIET NIPLQQGGRILCRGTHVYLGDDMPD PGLVLAGTKCADGKICLNRQCQNIS VFGVHECAMQCHGRGVCNNRKNCHC EAHWAPPFCDKFGFGGSTDSGPIRQ AGKEARQEAAESNRERGQGQEPVGS QEHASTASLTLI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ]
Official Symbol : ADAM12
Synonyms : ADAM12; ADAM metallopeptidase domain 12; a disintegrin and metalloproteinase domain 12 (meltrin alpha); disintegrin and metalloproteinase domain-containing protein 12; MCMPMltna; meltrin alpha; MLTN; meltrin-alpha; MCMP; MLTNA;
Gene ID : 8038
mRNA Refseq : NM_003474
Protein Refseq : NP_003465
MIM : 602714
UniProt ID : O43184

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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In addition to studies related to breast cancer, what other diseases is ADAD12 currently being used to study? 04/25/2022

Currently, ADAM12 is also involved in the study of lung cancer and liver cancer.

Does ADAM12 affect Vimentin expression? 09/03/2021

ADAM12 upregulates the expression of Vimentin.

Does ADAM12 interact with insulin-like growth factor-binding protein-3 (IGFBP)-3? 04/11/2021

ADAM12 interacts with insulin-like growth factor binding protein(IGFBP)-3.

I want to buy ADAM12-related proteins, do you provide other proteins? 11/15/2020

We offer myoferlin and Vimentin proteins in addition to ADAM12 proteins.

What protein does ADAM12 hydrolyze? 01/16/2020

ADAM12 protein can hydrolyze Delta-like 1、Ephrin-A1, etc.

What are the two conformations of ADAM12? 12/04/2019

The two conformations of ADAM are the membrane-penetrating full-length type (ADAM12-L) and the secretory type (ADAM12-S), respectively.

Customer Reviews (2)

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Reviews
08/22/2020

    The technical staff evaluated my experimental process and results and made many constructive comments

    05/28/2019

      Protein products are put into experiments with good effect and reliable experimental results

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