| Description : |
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
103.6 kDa |
| AA Sequence : |
MAEIKEKICDYLFNVSDSSALNLAK NIGLTKARDINAVLIDMERQGDVYR QGTTPPIWHLTDKKRERMQIKRNTN SVPETAPAAIPETKRNAEFLTCNIP TSNASNNMVTTEKVENGQEPVIKLE NRQEARPEPARLKPPVHYNGPSKAG YVDFENGQWATDDIPDDLNSIRAAP GEFRAIMEMPSFYSHGLPRCSPYKK LTECQLKNPISGLLEYAQFASQTCE FNMIEQSGPPHEPRFKFQVVINGRE FPPAEAGSKKVAKQDAAMKAMTILL EEAKAKDSGKSEESSHYSTEKESEK TAESQTPTPSATSFFSGKSPVTTLL ECMHKLGNSCEFRLLSKEGPAHEPK FQYCVAVGAQTFPSVSAPSKKVAKQ MAAEEAMKALHGEATNSMASDNQPE GMISESLDNLESMMPNKVRKIGELV RYLNTNPVGGLLEYARSHGFAAEFK LVDQSGPPHEPKFVYQAKVGGRWFP AVCAHSKKQGKQEAADAALRVLIGE NEKAERMGFTEVTPVTGASLRRTML LLSRSPEAQPKTLPLTGSTFHDQIA MLSHRCFNTLTNSFQPSLLGRKILA AIIMKKDSEDMGVVVSLGTGNRCVK GDSLSLKGETVNDCHAEIISRRGFI RFLYSELMKYNSQTAKDSIFEPAKG GEKLQIKKTVSFHLYISTAPCGDGA LFDKSCSDRAMESTESRHYPVFENP KQGKLRTKVENGEGTIPVESSDIVP TWDGIRLGERLRTMSCSDKILRWNV LGLQGALLTHFLQPIYLKSVTLGYL FSQGHLTRAICCRVTRDGSAFEDGL RHPFIVNHPKVGRVSIYDSKRQSGK TKETSVNWCLADGYDLEILDGTRGT VDGPRNELSRVSKKNIFLLFKKLCS FRYRRDLLRLSYGEAKKAARDYETA KNYFKKGLKDMGYGNWISKPQEEKN FYLCPVTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
