Recombinant Human ADGRE2 Protein, His-tagged
Cat.No. : | ADGRE2-240H |
Product Overview : | Recombinant Human ADGRE2 Protein with His tag was expressed in E. coli. |
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Description : | Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~55 kDa |
AA Sequence : | QDSRGCARWCPQDSSCVNATACRCN PGFSSFSEIITTPMETCDDINECAT LSKVSCGKFSDCWNTEGSYDCVCSP GYEPVSGAKTFKNESENTCQDVDEC QQNPRLCKSYGTCVNTLGSYTCQCL PGFKLKPEDPKLCTDVNECTSGQNP CHSSTHCLNNVGSYQCRCRPGWQPI PGSPNGPNNTVCEDVDECSSGQHQC DSSTVCFNTVGSYSCRCRPGWKPRH GIPNNQKDTVCEDMTFSTWTPPPGV HSQTLSRFFDKVQDLGRDYKPGLAN NTIQSILQALDELLEAPGDLETLPR LQQHCVASHLLDGLEDVLRGLSKNL SNGLLNFSYPAGTELSLEVQKQVDR SVTLRQNQAVMQLDWNQAQKSGDPG PSVVGLVSIPGMGKLLAEAPLVLEP EKQMLLHETHQGLLQDGSPILLSDV ISAFLSNNDTQNLSSPVTFTFSHRS VIPRQKVLCVFWEHGQNGCGHWATT GCSTIGTRDTSTICRCTHLSSFAVL MAHYDVQEEDPVLTVIT |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | ADGRE2 adhesion G protein-coupled receptor E2 [ Homo sapiens (human) ] |
Official Symbol : | ADGRE2 |
Synonyms : | ADGRE2; adhesion G protein-coupled receptor E2; VBU; CD97; EMR2; CD312; adhesion G protein-coupled receptor E2; CD97 antigen; EGF-like module-containing mucin-like hormone receptor-like 2; Leukocyte antigen CD97; egf-like module containing, mucin-like, hormone receptor-like 2 |
Gene ID : | 30817 |
mRNA Refseq : | NM_013447 |
Protein Refseq : | NP_038475 |
MIM : | 606100 |
UniProt ID : | Q9UHX3 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionADGRE2 plays a role in immune cell activation, migration, and adhesion through mechanisms involving [specific cellular processes or adhesion molecules].
Activation or inhibition of ADGRE2 has functional consequences on immune cell function and immune responses, impacting [specific immune cell activities or immune response outcomes].
ADGRE2 activates specific downstream signaling pathways, including [specific signaling cascades], which contribute to various cellular processes, such as [specific immune cell activation or migration].
ADGRE2 interacts with specific ligands or interacting partners, such as [specific molecules or cell surface receptors], leading to the modulation of its function.
The expression or activity of ADGRE2 can be modulated by pharmacological agents that target [specific receptors or signaling pathways], or through genetic manipulation using [specific genetic tools or techniques].
Deficiency or knockout of ADGRE2 in immune cells leads to observable changes in immune cell phenotypes or altered immune responses, characterized by [specific immune cell dysfunctions or immune response impairments].
ADGRE2 is implicated in specific diseases or pathological conditions, such as [specific autoimmune diseases or inflammatory disorders], where it contributes to [specific disease mechanisms or immune dysregulation].
ADGRE2 exhibits a [specific subcellular localization pattern], with localization primarily observed in [specific cellular compartments, such as plasma membrane or endosomes].
Under normal physiological conditions, the expression of ADGRE2 is tightly regulated and can be modulated in response to specific stimuli, such as [specific cytokines or inflammatory signals].
The ADGRE2 protein exhibits a specific expression pattern across various tissues and cell types, with higher levels observed in [specific tissues or cell populations].
Customer Reviews (2)
Write a reviewDemonstrates excellent stability and consistency in long-term storage.
Provides accurate and reproducible quantification of the target protein in mass spectrometry analysis.
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