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Recombinant Human ADIRF Protein, MYC/DDK-tagged

Cat.No. : ADIRF-1371H
Product Overview : Recombinant human ADIRF protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 7.7 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : adipogenesis regulatory factor [ Homo sapiens ]
Official Symbol : ADIRF
Synonyms : AFRO; apM-2; APM2; C10orf116
Gene ID : 10974
Protein Refseq : NP_006820

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◆ Recombinant Protein
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (11)

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Are ADIRF proteins being studied as potential therapeutic targets for metabolic disorders? 09/19/2022

Yes, ADIRF proteins are being studied as potential therapeutic targets for metabolic disorders such as obesity and type 2 diabetes. Developing drugs that target ADIRF proteins could have therapeutic potential in improving insulin sensitivity and glucose metabolism, and reducing the risk of metabolic disorders.

Are there any known side effects of ADIRF protein therapy? 06/21/2020

As ADIRF-based therapies are still in the early stages of development, their safety profile has not yet been fully established. It is possible that there may be side effects, but more research is needed to determine this.

How do ADIRF proteins work? 03/13/2020

ADIRF proteins inhibit the transformation of preadipocytes into mature adipocytes by interacting with certain signal transduction pathways.

Can measuring levels of ADIRF proteins be used for diagnosis or monitoring of metabolic disorders? 02/05/2020

There is ongoing research to evaluate whether measuring levels of ADIRF proteins can be used for diagnosis or monitoring of metabolic disorders. While ADIRF proteins have shown promise as potential targets for therapy, the clinical utility of measuring ADIRF levels for diagnosis or monitoring is still being investigated.

Are there any drugs currently available that target ADIRF proteins? 06/05/2018

At present, there are no drugs approved by regulatory agencies that specifically target ADIRF proteins. However, there are several compounds being developed that target the same pathways and mechanisms as ADIRF proteins. These drugs may have potential therapeutic benefits for metabolic disorders and other conditions associated with ADIRF dysregulation.

Are there any drugs based on ADIRF proteins currently available? 01/16/2018

No, there are no drugs based on ADIRF proteins currently on the market. However, several research studies have explored the potential of ADIRF-based therapies.

How do ADIRF proteins impact lipid metabolism? 12/10/2017

ADIRF proteins play a role in regulating lipid metabolism, specifically in the storage and mobilization of lipids in adipose tissue. Dysregulation of ADIRF proteins can lead to altered lipid storage and mobilization, which may contribute to the development of metabolic disorders such as obesity and type 2 diabetes.

Can ADIRF proteins be used to treat other diseases beyond obesity and diabetes? 12/03/2017

While the primary focus of research into ADIRF proteins has been on their potential use in treating metabolic disorders, some studies have also suggested a possible role in cancer and inflammation. However, further research is needed to explore these potential applications.

How do ADIRF proteins impact insulin sensitivity and glucose metabolism? 09/21/2017

Studies have shown that ADIRF proteins may impact insulin sensitivity and glucose metabolism through their effects on adipocyte differentiation and lipid metabolism. They may play a role in the regulation of adipokine secretion, which can influence systemic insulin sensitivity and glucose metabolism. Dysregulation of ADIRF proteins has been shown to be associated with metabolic disorders such as obesity and type 2 diabetes.

Can lifestyle changes such as exercise and diet affect ADIRF proteins? 03/01/2017

Yes, lifestyle changes such as exercise and diet can affect ADIRF proteins. Exercise has been shown to increase ADIRF protein expression, which may contribute to its beneficial effects on metabolism and insulin sensitivity. Similarly, dietary changes can also affect ADIRF protein expression and activity. For example, a high-fat diet has been shown to increase the expression of certain ADIRF proteins, while a low-calorie diet can decrease their expression.

Are there any genetic mutations associated with ADIRF proteins and metabolic disorders? 01/07/2016

Several genetic mutations have been identified in ADIRF-related genes that are associated with the development of metabolic disorders. For example, mutations in the ADIRF gene have been shown to be associated with an increased risk of obesity and insulin resistance. Other genetic mutations in ADIRF-related genes have also been linked to metabolic disorders such as type 2 diabetes and non-alcoholic fatty liver disease.

Customer Reviews (5)

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Reviews
02/23/2022

    The quality of the protein is exceptionally high, making it a perfect fit for my experimental requirements.

    10/25/2021

      The technical support is an added bonus, as it provides a safety net for any unforeseen complications that arise during the experiment.

      06/23/2019

        On top of that, the manufacturer's technical support is outstanding and I am confident that any issues and concerns that arise can be swiftly resolved with their help.

        10/08/2018

          With such a reliable and top-notch product, I can focus on my research objectives without worrying about the integrity and reliability of my primary raw material.

          09/19/2018

            Not only is the protein of superior quality, but it also boasts remarkable purity, consistency and stability, precisely what I need for my experiments.

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