Recombinant Human ADIRF Protein, MYC/DDK-tagged
Cat.No. : | ADIRF-1371H |
Product Overview : | Recombinant human ADIRF protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 7.7 kDa |
Purity : | >50 ug/mL as determined by microplate BCA method |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | adipogenesis regulatory factor [ Homo sapiens ] |
Official Symbol : | ADIRF |
Synonyms : | AFRO; apM-2; APM2; C10orf116 |
Gene ID : | 10974 |
Protein Refseq : | NP_006820 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (11)
Ask a questionYes, ADIRF proteins are being studied as potential therapeutic targets for metabolic disorders such as obesity and type 2 diabetes. Developing drugs that target ADIRF proteins could have therapeutic potential in improving insulin sensitivity and glucose metabolism, and reducing the risk of metabolic disorders.
As ADIRF-based therapies are still in the early stages of development, their safety profile has not yet been fully established. It is possible that there may be side effects, but more research is needed to determine this.
ADIRF proteins inhibit the transformation of preadipocytes into mature adipocytes by interacting with certain signal transduction pathways.
There is ongoing research to evaluate whether measuring levels of ADIRF proteins can be used for diagnosis or monitoring of metabolic disorders. While ADIRF proteins have shown promise as potential targets for therapy, the clinical utility of measuring ADIRF levels for diagnosis or monitoring is still being investigated.
At present, there are no drugs approved by regulatory agencies that specifically target ADIRF proteins. However, there are several compounds being developed that target the same pathways and mechanisms as ADIRF proteins. These drugs may have potential therapeutic benefits for metabolic disorders and other conditions associated with ADIRF dysregulation.
No, there are no drugs based on ADIRF proteins currently on the market. However, several research studies have explored the potential of ADIRF-based therapies.
ADIRF proteins play a role in regulating lipid metabolism, specifically in the storage and mobilization of lipids in adipose tissue. Dysregulation of ADIRF proteins can lead to altered lipid storage and mobilization, which may contribute to the development of metabolic disorders such as obesity and type 2 diabetes.
While the primary focus of research into ADIRF proteins has been on their potential use in treating metabolic disorders, some studies have also suggested a possible role in cancer and inflammation. However, further research is needed to explore these potential applications.
Studies have shown that ADIRF proteins may impact insulin sensitivity and glucose metabolism through their effects on adipocyte differentiation and lipid metabolism. They may play a role in the regulation of adipokine secretion, which can influence systemic insulin sensitivity and glucose metabolism. Dysregulation of ADIRF proteins has been shown to be associated with metabolic disorders such as obesity and type 2 diabetes.
Yes, lifestyle changes such as exercise and diet can affect ADIRF proteins. Exercise has been shown to increase ADIRF protein expression, which may contribute to its beneficial effects on metabolism and insulin sensitivity. Similarly, dietary changes can also affect ADIRF protein expression and activity. For example, a high-fat diet has been shown to increase the expression of certain ADIRF proteins, while a low-calorie diet can decrease their expression.
Several genetic mutations have been identified in ADIRF-related genes that are associated with the development of metabolic disorders. For example, mutations in the ADIRF gene have been shown to be associated with an increased risk of obesity and insulin resistance. Other genetic mutations in ADIRF-related genes have also been linked to metabolic disorders such as type 2 diabetes and non-alcoholic fatty liver disease.
Customer Reviews (5)
Write a reviewThe quality of the protein is exceptionally high, making it a perfect fit for my experimental requirements.
The technical support is an added bonus, as it provides a safety net for any unforeseen complications that arise during the experiment.
On top of that, the manufacturer's technical support is outstanding and I am confident that any issues and concerns that arise can be swiftly resolved with their help.
With such a reliable and top-notch product, I can focus on my research objectives without worrying about the integrity and reliability of my primary raw material.
Not only is the protein of superior quality, but it also boasts remarkable purity, consistency and stability, precisely what I need for my experiments.
Ask a Question for All ADIRF Products
Required fields are marked with *
My Review for All ADIRF Products
Required fields are marked with *
Inquiry Basket