Recombinant Human ADORA1, GST-tagged

• Cat.No.: ADORA1-9433H
• Product Overview: Recombinant Human ADORA1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 184-243a.a.
• Description: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5 UTR have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ADORA1 adenosine A1 receptor [ Homo sapiens ]
• Official Symbol: ADORA1
• Synonyms: ADORA1; adenosine A1 receptor; adenosine receptor A1; RDC7
• Gene ID: 134
• mRNA Refseq: NM_000674
• Protein Refseq: NP_000665
• MIM: 102775
• UniProt ID: P30542
• Chromosome Location: 1q32.1
• Pathway: Adenosine P1 receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Morphine addiction, organism-specific biosystem
• Function: G-protein beta/gamma-subunit complex binding; G-protein coupled adenosine receptor activity; G-protein coupled receptor binding; heterotrimeric G-protein binding; phospholipase C activity; protein binding; protein heterodimerization activity; purine nucle