Recombinant Human AEN Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human AEN Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : AEN-759H
Product Overview : AEN MS Standard C13 and N15-labeled recombinant protein (NP_073604) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 36.4 kDa
AA Sequence : MVPREAPESA QCLCPSLTIP NAKDVLRKRH KRRSRQHQRF MARKALLQEQ GLLSMPPEPG SSPLPTPFGA ATATEAASSG KQCLRAGSGS APCSRRPAPG KASGPLPSKC VAIDCEMVGT GPRGRVSELA RCSIVSYHGD VLYDKYIRPE MPIADYRTRW SGITRQHMRK AVPFQVAQKE ILKLLKGKVV VGHALHNDFQ ALKYVHPRSQ TRDTTYVPNF LSEPGLHTRA RVSLKDLALQ LLHKKIQVGQ HGHSSVEDAT TAMELYRLVE VQWEQQEARS LWTCPEDREP DSSTDMEQYM EDQYWPDDLA HGSRGGAREA QDRRNTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : AEN apoptosis enhancing nuclease [ Homo sapiens (human) ]
Official Symbol : AEN
Synonyms : AEN; apoptosis enhancing nuclease; interferon stimulated exonuclease gene 20kDa like 1, ISG20L1; apoptosis-enhancing nuclease; FLJ12484; FLJ12562; interferon-stimulated 20 kDa exonuclease-like 1; interferon stimulated exonuclease gene 20kDa-like 1; ISG20L1; pp12744;
Gene ID : 64782
mRNA Refseq : NM_022767
Protein Refseq : NP_073604
MIM : 610177
UniProt ID : Q8WTP8

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