Recombinant Human AGAP2 Protein, GST-tagged

• Cat.No.: AGAP2-417H
• Product Overview: Human AGAP2 full-length ORF ( AAH28020.1, 1 a.a. - 836 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 116.9 kDa
• AA Sequence: MHAQRQFVVAAVRAEVRRHEVAKQA LNRLRKLAERVDDPELQDSIQASLD SIREAVINSQEWTLSRSIPELRLGV LGDARSGKSSLIHRFLTGSYQVLEK TESEQYKKEMLVDGQTHLVLIREEA GAPDAKFSGWADAVIFVFSLEDENS FQAVSRLHGQLSSLRGEGRGGLALA LVGTQDRISASSPRVVGDARARALC ADMKRCSYYETCATYGLNVDRVFQE VAQKVVTLRKQQQLLAACKSLPSSP SHSAASTPVAGQASNGGHTSDYSSS LPSSPNVGHRELRAEAAAVAGLSTP GSLHRAAKRRTSLFANRRGSDSEKR SLDSRGETTGSGRAIPIKQSFLLKR SGNSLNKEWKKKYVTLSSNGFLLYH PSINDYIHSTHGKEMDLLRTTVKVP GKRPPRAISAFGPSASINGLVKDMS TVQMGEGLEATTPMPSPSPSPSSLQ PPPDQTSKHLLKPDRNLARALSTDC TPSGDLSPLSREPPPSPMVKKQRRK KLTTPSKTEGSAGQAEEENFEFLIV SSTGQTWHFEAASFEERDAWVQAIE SQILASLQCCESSKVKLRTDSQSEA VAIQAIRNAKGNSICVDCGAPNPTW ASLNLGALICIECSGIHRNLGTHLS RVRSLDLDDWPRELTLVLTAIGNDT ANRVWESDTRGRAKPSRDSSREERE SWIRAKYEQLLFLAPLSTSEEPLGR QLWAAVQAQDVATVLLLLAHARHGP LDTSVEDPQLRSPLHLAAELAHVVI TQLLLWYGADVAARDAQGRTALFYA RQAGSQLCADILLQHGCPGEGGSAA TTPSAATTPSITATPSPRRRSSAAS VGRADAPVALV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [ Homo sapiens ]
• Official Symbol: AGAP2
• Synonyms: AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; centaurin, gamma 1, CENTG1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; cnt-g1; centaurin, gamma 1; phosphoinositide 3-kinase enhancer; phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; GTP-binding and GTPase activating protein 2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; PIKE; GGAP2; CENTG1; FLJ16430; KIAA0167
• Gene ID: 116986
• mRNA Refseq: NM_001122772
• Protein Refseq: NP_001116244
• MIM: 605476
• UniProt ID: Q99490