Recombinant Human AKR7A2 Protein, GST-tagged

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Recombinant Human AKR7A2 Protein, GST-tagged

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Cat.No. : AKR7A2-418H
Product Overview : Human AKR7A2 full-length ORF ( AAH04111.3, 1 a.a. - 330 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 61.82 kDa
AA Sequence : MSRPPPPRVA SVLGTMEMGR RMDAPASAAA VRAFLERGHT ELDTAFMYSD GQSETILGGL GLGLGGGDCR VKIATKANPW DGKSLKPDSV RSQLETSLKR LQCPQVDLFY LHAPDHGTPV EETLHACQRL HQEGKFVELG LSNYASWEVA EICTLCKSNG WILPTVYQGM YNATTRQVET ELFPCLRHFG LRFYAYNPLA GGLLTGKYKY EDKDGKQPVG RFFGNSWAET YRNRFWKEHH FEAIALVEKA LQAAYGASAP SVTSAALRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA TEEGPLEPAV VDAFNQAWHL VAHECPNYFR
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) [ Homo sapiens ]
Official Symbol : AKR7A2
Synonyms : AKR7A2; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase); aflatoxin B1 aldehyde reductase member 2; AFAR; AFB1-AR 1; SSA reductase; aldoketoreductase 7; AFB1 aldehyde reductase 1; succinic semialdehyde reductase; aflatoxin beta1 aldehyde reductase; AKR7; AFAR1; AFB1-AR1;
Gene ID : 8574
mRNA Refseq : NM_003689
Protein Refseq : NP_003680
MIM : 603418
UniProt ID : O43488
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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