Recombinant Human ALDH1A2 protein, His & T7-tagged

• Cat.No.: ALDH1A2-1357H
• Product Overview: Recombinant Human ALDH1A2 aa. (Met1~Ser422 (Accession# O94788) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 49.8kDa
• Protein length: Met1~Ser422 (Accession# O94788)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 6.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ALDH1A2 aldehyde dehydrogenase 1 family member A2 [ Homo sapiens (human) ]
• Official Symbol: ALDH1A2
• Synonyms: ALDH1A2; aldehyde dehydrogenase 1 family member A2; RALDH2; RALDH2-T; RALDH(II); retinal dehydrogenase 2; RALDH 2; retinaldehyde-specific dehydrogenase type 2
• Gene ID: 8854
• mRNA Refseq: NM_001206897.1
• Protein Refseq: NP_001193826.1
• UniProt ID: O94788