Recombinant Human ALDH8A1 Protein, GST-tagged

• Cat.No.: ALDH8A1-453H
• Product Overview: Human ALDH8A1 full-length ORF ( NP_072090.1, 1 a.a. - 487 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 79.8 kDa
• AA Sequence: MAGTNALLMLENFIDGKFLPCSSYI DSYDPSTGEVYCRVPNSGKDEIEAA VKAAREAFPSWSSRSPQERSRVLNQ VADLLEQSLEEFAQAESKDQGKTLA LARTMDIPRSVQNFRFFASSSLHHT SECTQMDHLGCMHYTVRAPVGVAGL ISPWNLPLYLLTWKIAPAMAAGNTV IAKPSELTSVTAWMLCKLLDKAGVP PGVVNIVFGTGPRVGEALVSHPEVP LISFTGSQPTAERITQLSAPHCKKL SLELGGKNPAIIFEDANLDECIPAT VRSSFANQGEICLCTSRIFVQKSIY SEFLKRFVEATRKWKVGIPSDPLVS IGALISKAHLEKVRSYVKRALAEGA QIWCGEGVDKLSLPARNQAGYFMLP TVITDIKDESCCMTEEIFGPVTCVV PFDSEEEVIERANNVKYGLAATVWS SNVGRVHRVAKKLQSGLVWTNCWLI RELNLPFGGMKSSGIGREGAKDSYD FFTEIKTITVKH
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH8A1 aldehyde dehydrogenase 8 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH8A1
• Synonyms: ALDH8A1; aldehyde dehydrogenase 8 family, member A1; aldehyde dehydrogenase family 8 member A1; ALDH12; aldehyde dehydrogenase 12; aldehyde dehydrogenase family protein; DJ352A20.2; MGC138650; DKFZp779D2315
• Gene ID: 64577
• mRNA Refseq: NM_001193480
• Protein Refseq: NP_001180409
• MIM: 606467
• UniProt ID: Q9H2A2