Recombinant Human AMOT protein, GST-tagged

• Cat.No.: AMOT-528H
• Product Overview: Human AMOT full-length ORF ( NP_573572.1, 1 a.a. - 675 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 98.9 kDa
• AA Sequence: MPRAQPSSASYQPVPADPFAIVSRA QQMVEILSDENRNLRQELEGCYEKV ARLQKVETEIQRVSEAYENLVKSSS KREALEKAMRNKLEGEIRRMHDFNR DLRERLETANKQLAEKEYEGSEDTR KTISQLFAKNKESQREKEKLEAELA TARSTNEDQRRHIEIRDQALSNAQA KVVKLEEELKKKQVYVDKVEKMQQA LVQLQAACEKREQLEHRLRTRLERE LESLRIQQRQGNCQPTNVSEYNAAA LMELLREKEERILALEADMTKWEQK YLEENVMRHFALDAAATVAAQRDTT VISHSPNTSYDTALEARIQKEEEEI LMANKRCLDMEGRIKTLHAQIIEKD AMIKVLQQRSRKEPSKTEQLSCMRP AKSLMSISNAGSGLLSHSSTLTGSP IMEEKRDDKSWKGSLGILLGGDYRA EYVPSTPSPVPPSTPLLSAHSKTGS RDCSTQTERGTESNKTAAVAPISVP APVAAAATAAAITATAATITTTMVA AAPVAVAAAAAPAAAAAPSPATAAA TAAAVSPAAAGQIPAAASVASAAAV APSAAAAAAVQVAPAAPAPVPAPAL VPVPAPAAAQASAPAQTQAPTSAPA VAPTPAPTPTPAVAQAEVPASPATG PGPHRLSIPSLTCNPDKTDGPVFHS NTLERKTPIQILGQEPDAEMVEYLI
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AMOT angiomotin [ Homo sapiens ]
• Official Symbol: AMOT
• Synonyms: AMOT; angiomotin; KIAA1071; angiomotin p80 isoform; angiomotin p130 isoform
• Gene ID: 154796
• mRNA Refseq: NM_001113490
• Protein Refseq: NP_001106962
• MIM: 300410
• UniProt ID: Q4VCS5