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Recombinant Human ANGEL2 Protein, MYC/DDK-tagged

Cat.No. : ANGEL2-2081H
Product Overview : Recombinant human ANGEL2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 62.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ANGEL2 angel homolog 2 (Drosophila) [ Homo sapiens ]
Official Symbol : ANGEL2
Synonyms : Ccr4d; KIAA0759L
Gene ID : 90806
mRNA Refseq : NM_144567
Protein Refseq : NP_653168
UniProt ID : Q5VTE6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (12)

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What disorders or diseases are associated with ANGEL2? 01/18/2023

Currently, there are no known specific disorders or diseases directly associated with ANGEL2 mutations or dysregulation. However, some studies have indicated potential links between ANGEL2 and certain conditions, such as autism spectrum disorder and intellectual disability. Further research is needed to establish a definitive connection.

Are there any known interacting proteins or pathways associated with ANGEL2? 12/05/2022

Research exploring protein-protein interactions and pathways involving ANGEL2 is limited. However, some studies have suggested potential interactions with proteins involved in protein synthesis, RNA processing, and cellular growth. Future studies may provide more insights into the specific molecular interactions and pathways associated with ANGEL2.

Is ANGEL2 associated with any cellular signaling pathways? 08/15/2022

There is limited information available regarding the specific cellular signaling pathways in which ANGEL2 is involved. Further research is needed to determine its interactions with signaling molecules and pathways.

What are the known functions of ANGEL2? 07/06/2022

The exact functions of ANGEL2 are not well understood. However, some studies suggest that ANGEL2 may play a role in neurodevelopment and neuronal signaling. It has also been implicated in the regulation of neuronal migration, as well as in synaptic function and plasticity. Further research is needed to determine its precise functions and molecular mechanisms.

Is ANGEL2 conserved across different species? 03/20/2022

ANGEL2 is conserved in various species, including mammals, suggesting its importance in biological processes. However, the degree of conservation and functional relevance across species are areas that require further investigation.

Is there any ongoing research on ANGEL2? 08/30/2021

Research on ANGEL2 is ongoing, particularly in the context of neurodevelopmental disorders such as autism spectrum disorder and intellectual disability. Scientists are exploring its cellular function, interactions, and potential contributions to diseases. It is an area of active investigation, and new findings may emerge in the future.

Can ANGEL2 be targeted for therapeutic purposes? 03/28/2021

Due to the limited understanding of ANGEL2's function and involvement in diseases, there are currently no specific therapies targeting this protein. Further research is required to elucidate its role in cellular processes and potential therapeutic avenues.

Can ANGEL2 be targeted for therapeutic purposes? 01/16/2021

Given the limited understanding of ANGEL2 and its functions, it is currently unclear whether it can be targeted for therapeutic purposes. However, further research on ANGEL2's molecular mechanisms and its association with specific diseases may provide insights into potential therapeutic strategies in the future.

Are there any animal models available to study ANGEL2? 04/15/2019

At present, there are no known specific animal models specifically targeting ANGEL2. Generating animal models with ANGEL2 genetic modifications might help in understanding its function in vivo and the associated disease implications.

Are there any known genetic variants or mutations in the ANGEL2 gene? 12/03/2018

The ANGEL2 gene does have genetic variants and mutations, but their specific implications and associations with diseases are not well-defined. More research is needed to understand the potential impact of these genetic changes on ANGEL2 function and their involvement in diseases.

Does ANGEL2 have any known roles in disease? 07/14/2017

ANGEL2 has been associated with neurodevelopmental disorders such as autism spectrum disorder (ASD) and intellectual disability. Some genetic studies have identified rare variants or mutations in ANGEL2 in individuals with these disorders. However, the exact role of ANGEL2 in disease development and the underlying mechanisms remain to be fully elucidated.

Are there any known interactors or binding partners of ANGEL2? 03/02/2016

There is limited information on the interactors or binding partners of ANGEL2. However, some studies suggest that ANGEL2 may interact with proteins involved in neuronal development and synaptic function, such as NMDA receptors and GABA receptors. Further research is needed to characterize its binding partners and understand the functional implications of these interactions.

Customer Reviews (4)

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Reviews
10/17/2022

    ANGEL2 protein's utility in protein electron microscopy structure analysis is commendable.

    11/30/2021

      ANGEL2 protein is highly recommended for various research applications, including ELISA and protein electron microscopy structure analysis.

      12/31/2020

        It enables researchers to delve deeper into the intricacies of protein behavior and aids in advancing our knowledge in various fields, such as molecular biology, biochemistry, and structural biology.

        08/04/2016

          Structural biology researchers can leverage its properties to better understand the three-dimensional architecture and conformational changes of proteins, gaining valuable insights into their function and interactions.

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