| Description : |
This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
92.2 kDa |
| AA Sequence : |
MGEGGLPPAFQLLLRACDQGDTETA RRLLEPGAAEPAERGAEPEAGAEPA GAEVAGPGAAAAGAVGAPVPVDCSD EAGNTALQFAAAGGHEPLVRFLLRR GASVNSRNHYGWSALMQAARFGHVS VAHLLLDHGADVNAQNRLGASVLTV ASRGGHLGVVKLLLEAGAFVDHHHP SGEQLGLGGSRDEPLDITALMAAIQ HGHEAVVRLLMEWGADPNHAARTVG WSPLMLAALTGRLGVAQQLVEKGAN PDHLSVLEKTAFEVALDCKHRDLVD YLDPLTTVRPKTDEEKRRPDIFHAL KMGNFQLVKEIADEDPSHVNLVNGD GATPLMLAAVTGQLALVQLLVERHA DVDKQDSVHGWTALMQATYHGNKEI VKYLLNQGADVTLRAKNGYTAFDLV MLLNDPDTELVRLLASVCMQVNKDK GRPSHQPPLPHSKVRQPWSIPVLPD DKGGLKSWWNRMSNRFRKLKLMQTL PRGLSSNQPLPFSDEPEPALDSTMR AAPQDKTSRSALPDAAPVTKDNGPG STRGEKEDTLLTTMLRNGAPLTRLP SDKLKAVIPPFLPPSSFELWSSDRS RTRHNGKADPMKTALPQRASRGHPV GGGGTDTTPVRPVKFPSLPRSPASS ANSGNFNHSPHSSGGSSGVGVSRHG GELLNRSGGSIDNVLSQIAAQRKKA AGLLEQKPSHRSSPVGPAPGSSPSE LPASPAGGSAPVGKKLETSKRPPSG TSTTSKSTSPTLTPSPSPKGHTAES SVSSSSSHRQSKSSGGSSSGTITDE DELTGILKKLSLEKYQPIFEEQEVD MEAFLTLTDGDLKELGIKTDGSRQQ ILAAISELNAGKGRERQILQETIHN FHSSFESSASNTRAPGNSPCATRRL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
