Recombinant Human APCDD1 protein, GST-tagged

• Cat.No.: APCDD1-672H
• Product Overview: Human APCDD1 full-length ORF ( NP_694545.1, 1 a.a. - 514 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.2 kDa
• AA Sequence: MSWPRRLLLRYLFPALLLHGLGEGS ALLHPDSRSHPRSLEKSAWRAFKES QCHHMLKHLHNGARITVQMPPTIEG HWVSTGCEVRSGPEFITRSYRFYHN NTFKAYQFYYGSNRCTNPTYTLIIR GKIRLRQASWIIRGGTEADYQLHNV QVICHTEAVAEKLGQQVNRTCPGFL ADGGPWVQDVAYDLWREENGCECTK AVNFAMHELQLIRVEKQYLHHNLDH LVEELFLGDIHTDATQRMFYRPSSY QPPLQNAKNHDHACIACRIIYRSDE HHPPILPPKADLTIGLHGEWVSQRC EVRPEVLFLTRHFIFHDNNNTWEGH YYHYSDPVCKHPTFSIYARGRYSRG VLSSRVMGGTEFVFKVNHMKVTPMD AATASLLNVFNGNECGAEGSWQVGI QQDVTHTNGCVALGIKLPHTEYEIF KMEQDARGRYLLFNGQRPSDGSSPD RPEKRATSYQMPLVQCASSSPRAED LAEDSGSSLYGRAPGRHTWSLLLAA LACLVPLLHWNIRR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: APCDD1 adenomatosis polyposis coli down-regulated 1 [ Homo sapiens ]
• Official Symbol: APCDD1
• Synonyms: APCDD1; adenomatosis polyposis coli down-regulated 1; protein APCDD1; B7323; hypoptrichosis simplex; adenomatosis polyposis coli down-regulated 1 protein; HHS; HTS; DRAPC1; FP7019
• Gene ID: 147495
• mRNA Refseq: NM_153000
• Protein Refseq: NP_694545
• MIM: 607479
• UniProt ID: Q8J025