Recombinant Human APITD1 protein, GST-tagged

Species :	Human
Source :	Wheat Germ
Tag :	GST
Description :	Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]
Molecular Mass :	42.3 kDa
AA Sequence :	MEEEAETEEQQRFSYQQRLKAAVHYTVGCLCEEVALDKEMQFSKQTIAAISELTFRQCENFAKDLEMFARHAKRTTINTEDVKLLARRSNSLLKYITDKSEEIAQINLERKAQKKKKSEDGSKNSRQPAEAGVVESEN
Applications :	Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes :	Best use within three months from the date of receipt of this protein.
Storage :	Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer :	50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Name	CENPS centromere protein S [ Homo sapiens (human) ]
Official Symbol	CENPS
Synonyms	CENPS; centromere protein S; MHF1; APITD1; CENP-S; FAAP16; centromere protein S; FANCM associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa; apoptosis-inducing TAF9-like domain-containing protein 1; apoptosis-inducing, TAF9-like domain 1
Gene ID	378708
mRNA Refseq	NM_199294
Protein Refseq	NP_954988
MIM	609130
UniProt ID	Q8N2Z9