Recombinant Human APLNR Protein (M1-R330), Flag, His tagged

• Cat.No.: APLNR-0967H
• Product Overview: Recombinant Human Flag-BRIL-3C-APJ(M1-R330) (T177N, C325L, C326M)-10His Protein was expressed in Insect cell.

Specification

• Description: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure.
• Source: Insect cell
• Species: Human
• Tag: Flag,His
• Form: Liquid
• Protein Length: M1-R330
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 85%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 25 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 0.01% (w/v) DDM, 0.002% (w/v) CHS
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: APLNR apelin receptor [ Homo sapiens (human) ]
• Official Symbol: APLNR
• Synonyms: APLNR; apelin receptor; AGTRL1, angiotensin II receptor like 1; APJ; APJ (apelin) receptor; APJR; FLJ90771; APJ receptor; HG11 orphan receptor; angiotensin receptor-like 1; G protein-coupled receptor APJ; G-protein coupled receptor APJ; angiotensin II receptor-like 1; G-protein coupled receptor HG11; HG11; AGTRL1; FLJ96609; MGC45246
• Gene ID: 187
• mRNA Refseq: NM_005161
• Protein Refseq: NP_005152
• MIM: 600052
• UniProt ID: P35414