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Recombinant Human AQR Protein, MYC/DDK-tagged

Cat.No. : AQR-2585H
Product Overview : Recombinant Human AQR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 171.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AQR aquarius homolog (mouse) [ Homo sapiens ]
Official Symbol : AQR
Synonyms : fSAP164; IBP160
Gene ID : 9716
mRNA Refseq : NM_014691
Protein Refseq : NP_055506
MIM : 610548
UniProt ID : O60306

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (23)

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Can manipulating the AQR protein provide therapeutic benefits? 12/28/2022

Given its involvement in ribosome biogenesis, targeting the AQR protein or related pathways could potentially have therapeutic implications in disorders associated with aberrant ribosome assembly and protein synthesis. However, further investigation is needed to develop specific interventions.

Is the AQR protein conserved across different species? 12/12/2022

Yes, the AQR protein is highly conserved across various species, including humans, mice, and yeast. This conservation indicates its importance in fundamental cellular processes.

Can alterations in the AQR protein affect cellular function? 08/21/2022

Yes, as the AQR protein is crucial for ribosome biogenesis, any disturbances or mutations in the AQR gene or protein can disrupt normal cellular processes dependent on proper protein synthesis. This can potentially impact various cellular functions and lead to developmental or health issues.

Can alterations in the AQR protein affect cellular function? 08/21/2022

Yes, as the AQR protein is crucial for ribosome biogenesis, any disturbances or mutations in the AQR gene or protein can disrupt normal cellular processes dependent on proper protein synthesis. This can potentially impact various cellular functions and lead to developmental or health issues.

How is the AQR protein linked to intellectual disability? 07/25/2022

Mutations in the AQR gene have been found in individuals with syndromic intellectual disability. These mutations weaken the AQR protein's ability to carry out its normal functions, particularly in ribosome assembly, which can result in impaired intellectual development.

How is the AQR protein linked to intellectual disability? 07/25/2022

Mutations in the AQR gene have been found in individuals with syndromic intellectual disability. These mutations weaken the AQR protein's ability to carry out its normal functions, particularly in ribosome assembly, which can result in impaired intellectual development.

Does the AQR protein have any other functions besides ribosome biogenesis? 04/28/2022

While the primary role of the AQR protein is in ribosome biogenesis, recent studies suggest that it may also play a role in DNA damage response and repair pathways.

Are there any diseases associated with alterations in the AQR protein? 03/22/2021

Currently, there are no known specific diseases directly linked to alterations in the AQR protein. However, its involvement in ribosome biogenesis suggests potential implications in disorders related to abnormal protein synthesis.

Are there any known post-translational modifications of the AQR protein? 04/07/2020

While specific post-translational modifications of the AQR protein have not been extensively studied, it is known that phosphorylation can occur on other ribosomal assembly factors. Further research is needed to determine if the AQR protein undergoes any post-translational modifications.

Are there any known post-translational modifications of the AQR protein? 04/07/2020

While specific post-translational modifications of the AQR protein have not been extensively studied, it is known that phosphorylation can occur on other ribosomal assembly factors. Further research is needed to determine if the AQR protein undergoes any post-translational modifications.

Are there any ongoing research efforts focused on the AQR protein? 12/30/2019

Research on the AQR protein is ongoing, particularly regarding its precise role in ribosome biogenesis and its potential involvement in human diseases. Further studies aim to unravel the molecular mechanisms and functional significance of this protein.

Are there any known mutations in the AQR gene? 10/03/2019

Yes, mutations in the AQR gene have been identified in certain individuals with syndromic intellectual disability. These mutations can impair ribosome biogenesis and lead to cellular and developmental abnormalities.

How does the AQR protein contribute to ribosome biogenesis? 09/02/2019

The AQR protein binds to specific regions of rRNA and helps in forming ribosomal subunits by facilitating the incorporation of ribosomal proteins into the rRNA scaffold.

Are there any therapeutic approaches targeting the AQR protein? 06/26/2019

Currently, there are no specific therapeutic interventions targeting the AQR protein. However, understanding its role in ribosome biogenesis may provide insights into potential strategies for addressing disorders related to abnormal protein synthesis in the future.

Are there any therapeutic approaches targeting the AQR protein? 06/26/2019

Currently, there are no specific therapeutic interventions targeting the AQR protein. However, understanding its role in ribosome biogenesis may provide insights into potential strategies for addressing disorders related to abnormal protein synthesis in the future.

How is the AQR protein related to ribosomal RNA (rRNA)? 05/19/2019

The AQR protein is involved in the assembly of ribosomal subunits by helping to incorporate rRNA into the scaffold. It interacts with specific regions of rRNA and facilitates the incorporation of ribosomal proteins, contributing to the formation of functional ribosomes.

How is the AQR protein related to ribosomal RNA (rRNA)? 05/19/2019

The AQR protein is involved in the assembly of ribosomal subunits by helping to incorporate rRNA into the scaffold. It interacts with specific regions of rRNA and facilitates the incorporation of ribosomal proteins, contributing to the formation of functional ribosomes.

Can changes in the AQR protein levels affect overall protein synthesis in cells? 01/06/2019

Yes, alterations in the AQR protein levels can potentially disrupt ribosome biogenesis, leading to impaired protein synthesis. This can affect the production of essential proteins involved in various cellular processes, ultimately impacting overall protein synthesis.

Can changes in the AQR protein levels affect overall protein synthesis in cells? 01/06/2019

Yes, alterations in the AQR protein levels can potentially disrupt ribosome biogenesis, leading to impaired protein synthesis. This can affect the production of essential proteins involved in various cellular processes, ultimately impacting overall protein synthesis.

Are there any known interacting partners of the AQR protein? 07/31/2018

Yes, studies have identified several proteins that interact with the AQR protein during ribosome biogenesis. These include other ribosomal assembly factors, RNA helicases, and proteins involved in pre-rRNA processing.

Are there any known interacting partners of the AQR protein? 07/31/2018

Yes, studies have identified several proteins that interact with the AQR protein during ribosome biogenesis. These include other ribosomal assembly factors, RNA helicases, and proteins involved in pre-rRNA processing.

Can changes in the AQR protein expression levels be observed in certain diseases? 10/04/2017

While alterations in AQR protein expression levels have not been clearly linked to specific diseases, dysregulation of ribosome assembly factors, including AQR, has been implicated in various cancers and neurodegenerative disorders. Further research is needed to establish direct associations.

Can changes in the AQR protein expression levels be observed in certain diseases? 10/04/2017

While alterations in AQR protein expression levels have not been clearly linked to specific diseases, dysregulation of ribosome assembly factors, including AQR, has been implicated in various cancers and neurodegenerative disorders. Further research is needed to establish direct associations.

Customer Reviews (8)

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Reviews
03/25/2020

    the manufacturer can contribute to the research process by providing top-quality AQR protein that meets rigorous standards of purity, stability, and reliability.

    11/08/2019

      This unique capability to selectively bind to exposed PS simplifies the identification and quantification of different cellular populations, reducing experimental errors and enhancing accuracy.

      10/11/2019

        This may include providing detailed protocols, troubleshooting guidance, and access to knowledgeable experts who can answer any inquiries or concerns.

        03/12/2019

          This includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.

          03/03/2019

            They can provide technical assistance, ensuring optimal utilization of the product.

            11/24/2017

              By choosing the AQR protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.

              12/06/2016

                the AQR protein demonstrates exceptional stability, allowing for prolonged storage and usage without compromising its integrity.

                09/16/2016

                  The manufacturer of the AQR protein plays a crucial role in supporting researchers during their trials.

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