Recombinant Human ARHGAP25, GST-tagged

• Cat.No.: ARHGAP25-9821H
• Product Overview: Recombinant Human ARHGAP25 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-347a.a.
• Description: ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARHGAP25 Rho GTPase activating protein 25 [ Homo sapiens ]
• Official Symbol: ARHGAP25
• Synonyms: ARHGAP25; Rho GTPase activating protein 25; rho GTPase-activating protein 25; KIAA0053; rho-type GTPase-activating protein 25; KAIA0053
• Gene ID: 9938
• mRNA Refseq: NM_001007231
• Protein Refseq: NP_001007232
• MIM: 610587
• UniProt ID: P42331
• Chromosome Location: 2p13.3
• Pathway: Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem
• Function: GTPase activator activity