Recombinant Human ARPC1B protein, GST-tagged

• Cat.No.: ARPC1B-845H
• Product Overview: Human ARPC1B full-length ORF ( NP_005711.1, 1 a.a. - 372 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.3 kDa
• AA Sequence: MAYHSFLVEPISCHAWNKDRTQIAI CPNNHEVHIYEKSGAKWTKVHELKE HNGQVTGIDWAPESNRIVTCGTDRN AYVWTLKGRTWKPTLVILRINRAAR CVRWAPNENKFAVGSGSRVISICYF EQENDWWVCKHIKKPIRSTVLSLDW HPNNVLLAAGSCDFKCRIFSAYIKE VEERPAPTPWGSKMPFGELMFESSS SCGWVHGVCFSASGSRVAWVSHDST VCLADADKKMAVATLASETLPLLAL TFITDNSLVAAGHDCFPVLFTYDAA AGMLSFGGRLDVPKQSSQRGLTARE RFQNLDKKASSEGGTAAGAGLDSLH KNSVSQISVLSGGKAKCSQFCTTGM DGGMSIWDVKSLESALKDLKIK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa [ Homo sapiens ]
• Official Symbol: ARPC1B
• Synonyms: ARPC1B; actin related protein 2/3 complex, subunit 1B, 41kDa; actin related protein 2/3 complex, subunit 1B (41 kD); actin-related protein 2/3 complex subunit 1B; actin related protein 2/3 complex; subunit 1A (41 kD); ARC41; ARP2/3 protein complex subunit p41; p40 ARC; p41 ARC; arp2/3 complex 41 kDa subunit; p40-ARC; p41-ARC
• Gene ID: 10095
• mRNA Refseq: NM_005720
• Protein Refseq: NP_005711
• MIM: 604223
• UniProt ID: O15143