Recombinant Human ASTL Protein (24-431 aa), His-Myc-tagged

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Recombinant Human ASTL Protein (24-431 aa), His-Myc-tagged

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Cat.No. : ASTL-2574H
Product Overview : Recombinant Human ASTL Protein (24-431 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.
Description : Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Source : E. coli
Species : Human
Tag : His-Myc
Form : Tris-based buffer,50% glycerol
Molecular Mass : 50.6 kDa
Protein length : 24-431 aa
AA Sequence : APLASSCAGA CGTSFPDGLT PEGTQASGDK DIPAINQGLI LEETPESSFL IEGDIIRPSP FRLLSATSNK WPMGGSGVVE VPFLLSSKYD EPSRQVILEA LAEFERSTCI RFVTYQDQRD FISIIPMYGC FSSVGRSGGM QVVSLAPTCL QKGRGIVLHE LMHVLGFWHE HTRADRDRYI RVNWNEILPG FEINFIKSQS SNMLTPYDYS SVMHYGRLAF SRRGLPTITP LWAPSVHIGQ RWNLSASDIT RVLKLYGCSP SGPRPRGRGS HAHSTGRSPA PASLSLQRLL EALSAESRSP DPSGSSAGGQ PVPAGPGESP HGWESPALKK LSAEASARQP QTLASSPRSR PGAGAPGVAQ EQSWLAGVST KPTVPSSEAG IQPVPVQGSP ALPGGCVPRN HFKGMSED
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : ASTL astacin-like metallo-endopeptidase (M12 family) [ Homo sapiens ]
Official Symbol : ASTL
Synonyms : ASTL; astacin-like metallo-endopeptidase (M12 family); ovastacin; oocyte astacin; MGC129843;
Gene ID : 431705
mRNA Refseq : NM_001002036
Protein Refseq : NP_001002036
MIM : 608860
UniProt ID : Q6HA08
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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