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Recombinant Human ASTL Protein (24-431 aa), His-Myc-tagged

Cat.No. : ASTL-2574H
Product Overview : Recombinant Human ASTL Protein (24-431 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.
  • Specification
  • Gene Information
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Description : Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Source : E. coli
Species : Human
Tag : His-Myc
Form : Tris-based buffer,50% glycerol
Molecular Mass : 50.6 kDa
Protein length : 24-431 aa
AA Sequence : APLASSCAGACGTSFPDGLTPEGTQ ASGDKDIPAINQGLILEETPESSFL IEGDIIRPSPFRLLSATSNKWPMGG SGVVEVPFLLSSKYDEPSRQVILEA LAEFERSTCIRFVTYQDQRDFISII PMYGCFSSVGRSGGMQVVSLAPTCL QKGRGIVLHELMHVLGFWHEHTRAD RDRYIRVNWNEILPGFEINFIKSQS SNMLTPYDYSSVMHYGRLAFSRRGL PTITPLWAPSVHIGQRWNLSASDIT RVLKLYGCSPSGPRPRGRGSHAHST GRSPAPASLSLQRLLEALSAESRSP DPSGSSAGGQPVPAGPGESPHGWES PALKKLSAEASARQPQTLASSPRSR PGAGAPGVAQEQSWLAGVSTKPTVP SSEAGIQPVPVQGSPALPGGCVPRN HFKGMSED
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : ASTL astacin-like metallo-endopeptidase (M12 family) [ Homo sapiens ]
Official Symbol : ASTL
Synonyms : ASTL; astacin-like metallo-endopeptidase (M12 family); ovastacin; oocyte astacin; MGC129843;
Gene ID : 431705
mRNA Refseq : NM_001002036
Protein Refseq : NP_001002036
MIM : 608860
UniProt ID : Q6HA08

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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