| Description : |
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
100.21 kDa |
| AA Sequence : |
MSKNPSGKNRETVPIKDNFELEVLQ AQYKELKEKMKVMEEEVLIKNGEIK ILRDSLHQTESVLEEQRRSHFLLEQ EKTQALSDKEKEFSKKLQSLQSELQ FKDAEMNELRTKLQTSERANKLAAP SVSHVSPRKNPSVVIKPEACSPQFG KTSFPTKESFSANMSLPHPCQTESG YKPLVGREDSKLHSLRGDSIKQEEA QKSFVDSWRQRSNTQGSILINLLLK QPLIPGSSLSLCHLLSSSSESPAGT PLQPPGFGSTLAGMSGLRTTGSYDG SFSLSALREAQNLAFTGLNLVARNE CSRDGDPAEGGRRAFPLCQLPGAVH FLPLVQFFIGLHCQALQDLAAAKRS GAPGDSPTHSSCVSSGVETNPEDSV CILEGFSVTALSILQHLVCHSGAVV SLLLSGVGADSAAGEGNRSLVHRLS DGDMTSALRGVADDQGQHPLLKMLL HLLAFSSAATGHLQASVLTQCLKVL VKLAENTSCDFLPRFQCVFQVLPKC LSPETPLPSVLLAVELLSLLADHDQ LAPQLCSHSEGCLLLLLYMYITSRP DRVALETQWLQLEQEVVRALTVMLH RQWLTVRRAGGPPRTDQQRRTVRCL RDTVLLLHGLSQKDKLFMMHCVEVL HQFDQVMPGVSMLIRGLPDVTDCEE AALDDLCAAETDVEDPEVECG |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
