| Description : |
This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
141.4 kDa |
| AA Sequence : |
MVAAAAATEARLRRRTAATAALAGR SGGPHWDWDVTRAGRPGLGAGLRLP RLLSPPLRPRLLLLLLLLSPPLLLL LLPCEAEAAAAAAAVSGSAAAEAKE CDRPCVNGGRCNPGTGQCVCPAGWV GEQCQHCGGRFRLTGSSGFVTDGPG NYKYKTKCTWLIEGQPNRIMRLRFN HFATECSWDHLYVYDGDSIYAPLVA AFSGLIVPERDGNETVPEVVATSGY ALLHFFSDAAYNLTGFNITYSFDMC PNNCSGRGECKISNSSDTVECECSE NWKGEACDIPHCTDNCGFPHRGICN SSDVRGCSCFSDWQGPGCSVPVPAN QSFWTREEYSNLKLPRASHKAVVNG NIMWVVGGYMFNHSDYNMVLAYDLA SREWLPLNRSVNNVVVRYGHSLALY KDKIYMYGGKIDSTGNVTNELRVFH IHNESWVLLTPKAKEQYAVVGHSAH IVTLKNGRVVMLVIFGHCPLYGYIS NVQEYDLDKNTWSILHTQGALVQGG YGHSSVYDHRTRALYVHGGYKAFSA NKYRLADDLYRYDVDTQMWTILKDS RFFRYLHTAVIVSGTMLVFGGNTHN DTSMSHGAKCFSSDFMAYDIACDRW SVLPRPDLHHDVNRFGHSAVLHNST MYVFGGFNSLLLSDILVFTSEQCDA HRSEAACLAAGPGIRCVWNTGSSQC ISWALATDEQEEKLKSECFSKRTLD HDRCDQHTDCYSCTANTNDCHWCND HCVPRNHSCSEGQISIFRYENCPKD NPMYYCNKKTSCRSCALDQNCQWEP RNQECIALPENICGIGWHLVGNSCL KITTAKENYDNAKLFCRNHNALLAS LTTQKKVEFVLKQLRIMQSSQSMSK LTLTPWVGLRKINVSYWCWEDMSPF TNSLLQWMPSEPSDAGFCGILSEPS TRGLKAATCINPLNGSVCERPANHS AKQCRTPCALRTACGDCTSGSSECM WCSNMKQCVDSNAYVASFPFGQCME WYTMSTCPPENCSGYCTCSHCLEQP GCGWCTDPSNTGKGKCIEGSYKGPV KMPSQAPTGNFYPQPLLNSSMCLED SRYNWSFIHCPACQCNGHSKCINQS ICEKCENLTTGKHCETCISGFYGDP TNGGKCQPCKCNGHASLCNTNTGKC FCTTKGVKGDECQLCEVENRYQGNP LRGTCYYTLLIDYQFTFSLSQEDDR YYTAINFVATPDEQNRDLDMFINAS KNFNLNITWAASFSAGTQAGEEMPV VSKTNIKEYKDSFSNEKFDFRNHPN ITFFVYVSNFTWPIKIQVQTEQSGP TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
