| Description : |
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
56 kDa |
| AA Sequence : |
MRFHWLPTLSEPFDRNQELETCIRP LWTPSGSACETEHNKSMDMGNQHPS ISRLQEIQKEVKSVEQQVIGFSGLS DDKNYKKLERILTKQLFEIDSVDTE GKGDIQQARKRAAQETERLLKELEQ NANHPHRIEIQNIFEEAQSLVREKI VPFYNGGNCVTDEFEEGIQDIILRL THVKTGGKISLRKARYHTLTKICAV QEIIEDCMKKQPSLPLSEDAHPSVA KINFVMCEVNKARGVLIALLMGVNN NETCRHLSCVLSGLIADLDALDVCG RTEIRNYRREVVEDINKLLKYLDLE EEADTTKAFDLRQNHSILKIEKVLK RMREIKNELLQAQNPSELYLSSKTE LQGLIGQLDEVSLEKNPCIREARRR AVIEVQTLITYIDLKEALEKRKLFA CEEHPSHKAVWNVLGNLSEIQGEVL SFDGNRTDKNYIRLEELLTKQLLAL DAVDPQGEEKCKAARKQAVRLAQNI LSYLDLKSDEWEYTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
