Recombinant Human BCS1L Protein, MYC/DDK-tagged

• Cat.No.: BCS1L-2464H
• Product Overview: Recombinant Human BCS1L protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: BCS1L BCS1-like (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: BCS1L
• Synonyms: BCS; BCS1; BJS; FLNMS; GRACILE; h-BCS; Hs.6719; MC3DN1; PTD
• Gene ID: 617
• mRNA Refseq: NM_001079866
• Protein Refseq: NP_001073335
• MIM: 603647
• UniProt ID: Q9Y276