| Description : |
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy, and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
50.8 kDa |
| AA Sequence : |
MTTDERKLFNHLKSPHLKYWVPFIW FGNLATKARNEGRIRDSVDLQSLMT EMNRYRSWCSLLFGYDWVGIPLVYT QVAEQLINPFGEDDDDFETNWCIDR NLQVSLLAVDEMHMSLPKMKKDIYW DDSAARPPYTLAAADYCIPSFLGST VQMGLSGSDFPDEEWLWDYEKHGHR HSMIRRVKRFLSAHEHPSSPRRRSY RRQTSDSSMFLPRDDLSPARDLLDV PSRNPPRASPTWKKSCFPEGSPTLH FSMGELSTIRETSQTSTLQSLTPQS SVRTSPIKMPLVPEVLITAAEAPVP TSGGYHHDSATSILSSEFTGVQPSK TEQQQGPMGSILSPSEKETPPGGPS PQTVSASAEENIFNCEEDPGDTFLK RWSLPGFLGSSHTSLGNLSPDPMSS QPALLIDTETSSEISGINIVAGSRV SSDMLYLMENLDTKETDIIELNKET EESPKTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
