Description : |
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : |
Wheat Germ |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
84.92 kDa |
AA Sequence : |
MYENECECQLLLKEMLERLNKEADE ALLHNLRLQLEAQFLQDDISAAKDR HKKNLLEVQTYISILQQIIHTTPPA SIVTSGMREEKLLTEREVAALRSQL EEGREVLSHLQAQRVELQAQTTTLE QAIKSAHECYDDEIQLYNEQIETLR KEIEETERVLEKSSYDCRQLAVAQQ TLKNELDRYHRIIEIEGNRLTSAFI ETPIPLFTQSHGVSLSTGSGGKDLT RALQDITAAKPRQKALPKNVPRRKE IITKDKTNGALEDAPLKGLEDTKLV QVVLKEESESKFESESKEVSPLTQE GAPEDVPDGGQISKGFGKLYRKVKE KVRSPKEPETPTELYTKERHVLVTG DANYVDPRFYVSSITAKGGVAVSVA EDSVLYDGQVGPSPESPKPPLENGQ VGLQEKEDGQPIDQQPIDKEIEPDG AELEGPEEKREGEERDEESRRPCAM VTPGAEEPSIPEPPKPAADQDGAEV LGTRSRSLPEKGPPKALAYKTVEVV ESIEKISTESIQTYEETAVIVETMI GKTKSDKKKSGEKSS |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |