Recombinant Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 2, His-tagged

• Cat.No.: BLOC1S2-6767H
• Product Overview: Recombinant humanBLOC1S2 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: BLOC1S2 (Biogenesisof lysosome-related organelles complex 1 subunit 2) belongs to the BLOC1S2family. BLOC-1 or biogenesis of lysosome-related organelles complex 1 is aubiquitously expressed multisubunit protein complex. BLOC-1 is required fornormal biogenesis of specialized organelles of the endosomal-lysosomalsystem, such as melanosomes and platelet dense granules. This protein plays arole in cell proliferation.
• Form: Liquid. In 20 mM Tris-HClbuffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
• Molecular Weight: 18.5kDa (166aa),confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 85% by SDS -PAGE
• Concentration: 1mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMAAAAE GVLATRSDEP ARDDAAVETA EEAKEPAEAD ITELCRDMFS KMATYLTGELTATSEDYKLL ENMNKLTSLK YLEMKDIAIN ISRNLKDLNQ KYAGLQPYLD QINVIEEQVA ALEQAAYKLDAYSKKLEAKY KKLEKR
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Official Symbol: BLOC1S2
• Synonyms: BLOC1S2;biogenesis of lysosomal organelles complex-1, subunit 2; BLOS2;RP11-316M21.4; biogenesis of lysosome-related organelles complex 1 subunit 2;BLOC-1 subunit 2; centrosomal 10 kDa protein; centrosome protein oncogene;centrosome-associated protein; FLJ30135, MGC10120; CEAP; OTTHUMP00000020281;centrosomal 10 kDa protein; OTTHUMP00000020282
• Gene ID: 282991
• mRNA Refseq: NM_173809
• Protein Refseq: NP_776170
• MIM: 609768
• UniProt ID: Q6QNY1
• Chromosome Location: 10q24.31
• Function: gamma-tubulin binding; protein C-terminusbinding; protein binding