Recombinant Human BIRC5 Protein, Myc/DDK-tagged, C13 and N15-labeled BIRC5-5592H

Recombinant Human BIRC5 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : BIRC5-5592H Optional Service: Optional requirements on this protein
Product Overview : BIRC5/Survivin MS Standard C13 and N15-labeled recombinant protein (NP_001159) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 16.2 kDa
AA Sequence : MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK KKEFEETAKK VRRAIEQLAA MDTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BIRC5 baculoviral IAP repeat containing 5 [ Homo sapiens (human) ]
Official Symbol : BIRC5
Synonyms : BIRC5; baculoviral IAP repeat containing 5; API4, apoptosis inhibitor 4, baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing protein 5; EPR 1; survivin; survivin variant 3 alpha; apoptosis inhibitor 4; apoptosis inhibitor survivin; API4; EPR-1;
Gene ID : 332
mRNA Refseq : NM_001168
Protein Refseq : NP_001159
MIM : 603352
UniProt ID : O15392
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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